Unique ID issued by UMIN | UMIN000011263 |
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Receipt number | R000011082 |
Scientific Title | Impact of Sitagliptin on the Progression of Coronary Atherosclerosis in Diabetes Patients with Angina Pectoris |
Date of disclosure of the study information | 2013/08/01 |
Last modified on | 2019/01/28 05:55:25 |
Impact of Sitagliptin on the Progression of Coronary Atherosclerosis in Diabetes Patients with Angina Pectoris
Sitagliptin and coronary atherosclerosis
Impact of Sitagliptin on the Progression of Coronary Atherosclerosis in Diabetes Patients with Angina Pectoris
Sitagliptin and coronary atherosclerosis
Japan |
Diabetic patients with angina pectoris scheduled underwent percutaneous coronary intervention with drug eluting stent.
Cardiology |
Others
NO
The aim of this study is to investigate the effect of sitagliptin on coronary atherosclerosis.
Efficacy
Changes in plaque volume of coronary atherosclerosis assessed by intravascular ultrasound and plaque characteristics assessed by optical coherence tomography
Interventional
Parallel
Randomized
Individual
Open -no one is blinded
Active
NO
NO
Institution is not considered as adjustment factor.
NO
Numbered container method
2
Treatment
Medicine |
Sitagliptin treatment group;
Clinical investigators will initiate sitagliptin treatment after PCI
Sitaglitptin non-treatment group;
Clinical investigators will treat with oral antidiabetic agents except for sitagliptin
20 | years-old | <= |
85 | years-old | >= |
Male and Female
1)Type2 diabetes
2)Stable angina pectoris with scheduled PCI
3)PCI with drug-eluting stent
4)informed consent for participation in the study
1)Acute myocardial infarction and cardiogenic shock
2)PCI for left main trunk
3)Type1 diabetes
4)Severe ketosis and coma with in 6 months
5)Severe renal deficiency 6)Hemodyalysis
7)Treatment with immunosuppresant
8)Treatment with pioglitazone, glynide and insulin
9)Treatment with DPP4 except for sitagliptin
10)Hypersensitivity to sitagliptin
11)Pregnant and possible pregnat women
12)Malignancy
13)Judged as ineligible by clinical investigators
50
1st name | |
Middle name | |
Last name | Minoru Yoshiyama |
Osaka City University Graguate School of Medicine
Cardiovascular Medcine
1-4-3 Asahi-machi, Abeno-ku, Osaka City
1st name | |
Middle name | |
Last name |
Osaka City University Graguate School of Medicine
Cardiovascular Medcine
1-4-3 Asahi-machi, Abeno-ku, Osaka City
Osaka City University
Osaka City University
Non profit foundation
NO
2013 | Year | 08 | Month | 01 | Day |
Unpublished
Enrolling by invitation
2012 | Year | 07 | Month | 01 | Day |
2013 | Year | 05 | Month | 01 | Day |
2013 | Year | 07 | Month | 24 | Day |
2019 | Year | 01 | Month | 28 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000011082
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