Unique ID issued by UMIN | UMIN000009520 |
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Receipt number | R000011182 |
Scientific Title | Safety and efficacy of external application of Non-Steroidal Anti-Inflammatory Drugs(NSAIDs) with renal function in patients of type 2 diabetic nephropathy |
Date of disclosure of the study information | 2012/12/11 |
Last modified on | 2012/12/11 14:11:05 |
Safety and efficacy of external application of Non-Steroidal Anti-Inflammatory Drugs(NSAIDs) with renal function in patients of type 2 diabetic nephropathy
Effect of NSAIDs external application in type 2 diabetic nephropathy patients
Safety and efficacy of external application of Non-Steroidal Anti-Inflammatory Drugs(NSAIDs) with renal function in patients of type 2 diabetic nephropathy
Effect of NSAIDs external application in type 2 diabetic nephropathy patients
Japan |
Diabetic nephropathy
Endocrinology and Metabolism | Nephrology |
Others
NO
The short-term influence of the external application NSAIDs for renal function in a patients of diabetic nephropathy with lumbago and an articulatio-genus pain is considered.
Safety,Efficacy
Concentration of urinary Prostaglandin E2, serum loxoprofen(trans-OH body), estimated GFR(ml/min/m2),serum cystatin C,blood pressure and VAS(visual analogue scale).
Before and five days after consecutive external application,respectively
Interventional
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
1
Treatment
Medicine |
There was no placebo group. Only one group used loxoprofen.
20 | years-old | <= |
80 | years-old | > |
Male and Female
Patients of diabetic nephropathy(from stage II to IV)
Patients with Lunbago or knee pain.
Patients who take NSAIDs.
Patients for less than one month after an operation.
Patients who severe liver dysfunction and severe heart failure.
The patient who has hypersensitivity to loxoprofen.
The patient of aspirin-induced asthma.
22
1st name | |
Middle name | |
Last name | Takashi Uzu |
Shiga University of Medical Science
Internal medicine
Tsukinowa-Cho, Seta, Otsu, Shiga 520-2192, Japan
1st name | |
Middle name | |
Last name | Hisazumi Araki |
Shiga University of Medical Science
Internal medicine
haraki@belle.shiga-med.ac.jp
Shiga University of Medical Science
Shiga University of Medical Science
Self funding
NO
2012 | Year | 12 | Month | 11 | Day |
Unpublished
Completed
2010 | Year | 11 | Month | 01 | Day |
2010 | Year | 12 | Month | 16 | Day |
2011 | Year | 12 | Month | 31 | Day |
2011 | Year | 12 | Month | 31 | Day |
2012 | Year | 01 | Month | 31 | Day |
2012 | Year | 06 | Month | 30 | Day |
2012 | Year | 12 | Month | 11 | Day |
2012 | Year | 12 | Month | 11 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000011182
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