Unique ID issued by UMIN | UMIN000010693 |
---|---|
Receipt number | R000011383 |
Scientific Title | Investigation for the effects of hydrogen rich water on chronic hepatitis and liver cirrhosis |
Date of disclosure of the study information | 2013/05/20 |
Last modified on | 2017/05/14 12:54:10 |
Investigation for the effects of hydrogen rich water on chronic hepatitis and liver cirrhosis
Hydrogen rich water for chronic hepatitis
Investigation for the effects of hydrogen rich water on chronic hepatitis and liver cirrhosis
Hydrogen rich water for chronic hepatitis
Japan |
Chronic hepatitis and liver cirrhosis
Hepato-biliary-pancreatic medicine |
Others
NO
To investigate whether hydrogen rich water reduces oxidative stress and elevated ALT levels.
Efficacy
Reduction of high ALT
Interventional
Cross-over
Randomized
Open -no one is blinded
No treatment
2
Treatment
Food |
GroupA:drink hydrogen rich water 1L/day for 1month, following 1month washout and drink control water 1L/day for 1month.
GroupB:drink control water 1L/day for 1month, following 1 month washout and drink hydrogen rich water 1L/day for a month.
20 | years-old | <= |
80 | years-old | >= |
Male and Female
1)chronic hepatitis or liver cirrhosis diagnosed with liver biopsy or radiography and show ALT elevation with standard therapy.
2)Patients whose ALT levels kept beyond upper limit of normal range for more than 2 months.
1)Patients who need albumin administration more than once /week for 1 month or more.
2)Patients with edema or ascite.
3)Patients with hepatic encephalopathy.
4)Bilirubin levels equal or >2mg/dl.
5)Albumin levels <3g/dl.
6)Serum Na <130 mEq/L
7)Alcohol abuser.
8)Creatinin equal or >1.3mg/dl.
9)Patients who are receiving interferon treatment.
10)Family Doctors comment
20
1st name | |
Middle name | |
Last name | Akinobu Takaki |
Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences.
Department of Gastroenterology and Hepatology
2-5-1Shikata Cho, Kita-Ku, Okayama City, 700-8558Japan
086-235-7219
akitaka@md.okayama-u.ac.jp
1st name | |
Middle name | |
Last name | Akinobu Takaki |
Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences.
Department of Gastroenterology and Hepatology
2-5-1Shikata Cho, Kita-Ku,Okayama City
086-235-7219
akitaka@md.okayama-u.ac.jp
Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences.Department of Gastroenterology and Hepatology
Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences.Department of Gastroenterology and Hepatology
Self funding
NO
2013 | Year | 05 | Month | 20 | Day |
Unpublished
Terminated
2013 | Year | 01 | Month | 29 | Day |
2013 | Year | 02 | Month | 01 | Day |
2017 | Year | 12 | Month | 31 | Day |
2018 | Year | 03 | Month | 31 | Day |
2018 | Year | 03 | Month | 31 | Day |
2018 | Year | 09 | Month | 30 | Day |
2013 | Year | 05 | Month | 11 | Day |
2017 | Year | 05 | Month | 14 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000011383
Research Plan | |
---|---|
Registered date | File name |
Research case data specifications | |
---|---|
Registered date | File name |
Research case data | |
---|---|
Registered date | File name |