Unique ID issued by UMIN | UMIN000009817 |
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Receipt number | R000011503 |
Scientific Title | Randomized controlled trial of febuxostat and allopurinol on chronic heart failure patients with hyperuricemia |
Date of disclosure of the study information | 2013/01/20 |
Last modified on | 2019/08/01 11:57:34 |
Randomized controlled trial of febuxostat and allopurinol on chronic heart failure patients with hyperuricemia
Comparison of the effect of hyperuricemic drug on chronic heart failure patients
Randomized controlled trial of febuxostat and allopurinol on chronic heart failure patients with hyperuricemia
Comparison of the effect of hyperuricemic drug on chronic heart failure patients
Japan |
Chronic heart failure with hyperuricemia
Medicine in general | Cardiology | Nephrology |
Geriatrics |
Others
NO
The purpose of this study is to compare the relation of anti-oxidative stress effect and prognostic improvement of choronic heart failure patients between febuxostat and allopurinol.
Safety,Efficacy
Cardiac death and rehospitalization due to worsening heart failure
Interventional
Parallel
Randomized
Individual
Open -no one is blinded
Active
YES
YES
Institution is considered as adjustment factor in dynamic allocation.
YES
Numbered container method
2
Treatment
Medicine |
Febuxostat:250
Period: 2012.12-2016.3
allopurinol:250
Period: 2012.12-2016.3
20 | years-old | <= |
100 | years-old | >= |
Male and Female
1.Chronic heart failure patients with hyperuricemia
2.Stable outpatients (NYHA I-III)
1.Acute heart failure patients or acute myocardial infarction patients
2.Patients with renal failure (over Cr 2.0 mg/dl)
3.Patients who had already anti-hyperuricemic drug
4.Patietns with hypersensitivity of study drug
5.Pregnant woman
500
1st name | Yasuchika |
Middle name | |
Last name | Yasuchika |
Fukushima Medical University
Deaprtment of Cardiovascular Medicine
960-1295
1 Hikarigaoka, Fukushima
024-547-1190
takeishi@fmu.ac.jp
1st name | Satoshi |
Middle name | |
Last name | Suzuki |
Fukushima Medical University
Department of Cardiovascular Medicine
960-1295
1 Hikarigaoka, Fukushima
024-547-1190
ssatoshi@fmu.ac.jp
Deaprtment of Cardiovascular Medicine, Fukushima Medical University.
Japan Heart Foundation
Non profit foundation
Clinical Reserch Center, Fukushima Medical University
1 Hikarigaoka, Fukushima
024-547-1772
ssatoshi@fmu.ac.jp
NO
2013 | Year | 01 | Month | 20 | Day |
Unpublished
263
Completed
2012 | Year | 12 | Month | 01 | Day |
2012 | Year | 05 | Month | 28 | Day |
2012 | Year | 12 | Month | 01 | Day |
2018 | Year | 12 | Month | 31 | Day |
2019 | Year | 01 | Month | 31 | Day |
2019 | Year | 03 | Month | 31 | Day |
2019 | Year | 12 | Month | 31 | Day |
2013 | Year | 01 | Month | 20 | Day |
2019 | Year | 08 | Month | 01 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000011503
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