Unique ID issued by UMIN | UMIN000009902 |
---|---|
Receipt number | R000011603 |
Scientific Title | Effect of ornithine on blood and transdermal secretion of ammonia and on muscle fatigue |
Date of disclosure of the study information | 2013/01/30 |
Last modified on | 2013/01/30 11:24:26 |
Effect of ornithine on blood and transdermal secretion of ammonia and on muscle fatigue
Effect of ornithine on ammonia reduction
Effect of ornithine on blood and transdermal secretion of ammonia and on muscle fatigue
Effect of ornithine on ammonia reduction
Japan |
Healthy adult
Adult |
Others
NO
To examine the effect of ornithine intake on blood and transdermal secretion of ammonia before and after incremental exercise in healthy adult.
Efficacy
Blood ammonia, transdermal secretion of ammonia
Blood glucose, lactate, urea nitrogen, lactate dehydrogenase, creatine phosphokinase
Interventional
Cross-over
Randomized
Double blind -all involved are blinded
Placebo
2
Prevention
Food |
Single ingestion of ornithine 2.4 g followed by single ingestion of placebo
Single ingestion of placebo followed by single ingestion of ornithine 2.4 g
20 | years-old | <= |
40 | years-old | > |
Male
1)Male subjects between 20 and 40 year of age at the time of consent
2)Subjects with regular exercise about once a week, less than six times a month
3)Non-smoker
1)Subjects who regularly take ornithine supplements.
2)Subjects who aware perspire freely or modestly after moderate exercise.
3)Subjects who have illness under medical treatment.
4)Subjects who may possibly develop
allergic reactions associated with the test products
5) Subjects who have critical disease history such as diabetes, hepatic disorder, kidney disorder, cardiac disorder.
6)Subjects who are considered inappropriate by the result of selection visit
7)Subjects who participate in another clinical study at the beginning of this study
8)Subjects who are judged not appropriate for this study by study physician
20
1st name | |
Middle name | |
Last name | Yutaka Miura |
Kirin Co., Ltd.
Research laboratories for health science & food technologies
1-13-5, Fukuura Kanazawa Yokohama Japan
1st name | |
Middle name | |
Last name | Takeshi Kokubo |
Kirin Co., Ltd.
Research laboratories for health science & food technologies
1-13-5, Fukuura Kanazawa Yokohama Japan
Kirin Co., Ltd.
None
Self funding
NO
2013 | Year | 01 | Month | 30 | Day |
Unpublished
Completed
2010 | Year | 09 | Month | 07 | Day |
2010 | Year | 09 | Month | 17 | Day |
2010 | Year | 10 | Month | 18 | Day |
2013 | Year | 01 | Month | 30 | Day |
2013 | Year | 01 | Month | 30 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000011603
Research Plan | |
---|---|
Registered date | File name |
Research case data specifications | |
---|---|
Registered date | File name |
Research case data | |
---|---|
Registered date | File name |