Unique ID issued by UMIN | UMIN000010033 |
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Receipt number | R000011736 |
Scientific Title | To investigate the efficacy of tocilizumab in RA patients with moderate disease activity under biologic therapy |
Date of disclosure of the study information | 2013/02/14 |
Last modified on | 2018/09/13 11:05:58 |
To investigate the efficacy of tocilizumab in RA patients with moderate disease activity under biologic therapy
To investigate the efficacy of tocilizumab in RA patients with moderate disease activity
To investigate the efficacy of tocilizumab in RA patients with moderate disease activity under biologic therapy
To investigate the efficacy of tocilizumab in RA patients with moderate disease activity
Japan |
Rheumatoid Arthritis
Clinical immunology | Orthopedics |
Others
NO
To investigate the remission or low disease activity of tocilizumab therapy in RA patients with moderate disease activity under biologic therapy.
Safety,Efficacy
Low disease activity rate at 24 weeks (SDAI)
Interventional
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
1
Treatment
Medicine |
Tocilizumab (8 mg/kg of body weight) is to be infused every 4 weeks.
20 | years-old | <= |
75 | years-old | > |
Male and Female
1)Patients between 20 and 75 years old
2)Patients with rheumatoid arthritis
3)Patients with low to moderate activity activity under more than 24 weeks of anti-tumour necrosis factor biologic therapy
4)Moderate disease activity by SDAI
5)The patient by whom consent is got in written form about participation of the final examination
1)Patients who have serious infection
2)Patients who have history of severe allergic or anaphylactic reactions to human, humanized or murine monoclonal antibodies
3)Patients who have history of a malignant tumor, or who have malignant tumor
4)Patients who have serious cardiac disease or liver disease, renal damage
5)Pregnant women or women trying to get pregnant
6)Patients considered inappropriate judged by attending physicians
20
1st name | |
Middle name | |
Last name | Daihei Kida |
Nagoya Medical Center, National Hospital Organization in Japan
Department of Orthopaedic Surgery and Rheumatology
4-1-1 Sannomaru,Naka-ku Nagoya Aichi 460-0001, Japan
1st name | |
Middle name | |
Last name |
Nagoya Medical Center, National Hospital Organization in Japan
Department of Orthopaedic Surgery and Rheumatology
4-1-1 Sannomaru,Naka-ku Nagoya Aichi 460-0001, Japan
Daihei Kida
Nagoya Medical Center, National Hospital Organization in Japan
Self funding
NO
2013 | Year | 02 | Month | 14 | Day |
Unpublished
Terminated
2013 | Year | 01 | Month | 28 | Day |
2013 | Year | 02 | Month | 14 | Day |
2013 | Year | 02 | Month | 14 | Day |
2018 | Year | 09 | Month | 13 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000011736
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