Unique ID issued by UMIN | UMIN000010863 |
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Receipt number | R000012717 |
Scientific Title | The effect of CYP2C19 polymorphism on Japanese patients simultaneously receiving calcineurin inhibitor and voriconazole post hematopoietic stem cell transplant |
Date of disclosure of the study information | 2013/06/03 |
Last modified on | 2013/12/03 22:02:14 |
The effect of CYP2C19 polymorphism on Japanese patients simultaneously receiving calcineurin inhibitor and voriconazole post hematopoietic stem cell transplant
The effect of CYP2C19 polymorphism on VRCZ metabolism
The effect of CYP2C19 polymorphism on Japanese patients simultaneously receiving calcineurin inhibitor and voriconazole post hematopoietic stem cell transplant
The effect of CYP2C19 polymorphism on VRCZ metabolism
Japan |
hematopoietic diseases
Hematology and clinical oncology |
Malignancy
YES
To evaluate the effect of CYP2C19 polymorphism on the blood concentration level of calcineurin inhibitors and voriconazole in patients receiving hematopoietic stem cell transplant.
Pharmacokinetics
To evaluate the effect of CYP2C19 polymorphism on the blood concentration level of calcineurin inhibitors and voriconazole
Observational
20 | years-old | <= |
65 | years-old | > |
Male and Female
1) Age over 20-years-old and less than 65-years-old at the time of obtaining informed consent
2) Patients scheduled to use calcineurin inhibitors
3) Patients who have given written informed consent before stem cell transplant
1) Patients with allergic reaction to calcineurin inhibitors or voriconazole
2) Any other patient, whom the treating physician has declared inappropriate for study enrollment
55
1st name | |
Middle name | |
Last name | Shinichiro Okamoto |
Keio University School of Medicine
Division of Hematology
35 Shinanomachi, Shinjuku-ku, Tokyo
+81-3-3353-1211
okamoto@a7.keio.jp
1st name | |
Middle name | |
Last name | Yuya Kohda |
Keio University School of Medicine
Division of Hematology
35 Shinanomachi, Shinjuku-ku, Tokyo
+81-3-3353-1211
koukouda@gmail.com
Keio University School of Medicine, Divison of Hematology
Japan Research Foundation for Clinical Pharmacology
Non profit foundation
NO
2013 | Year | 06 | Month | 03 | Day |
Unpublished
Enrolling by invitation
2013 | Year | 04 | Month | 06 | Day |
2013 | Year | 06 | Month | 03 | Day |
Initiated enrollment
2013 | Year | 06 | Month | 03 | Day |
2013 | Year | 12 | Month | 03 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000012717
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