Unique ID issued by UMIN | UMIN000011985 |
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Receipt number | R000013069 |
Scientific Title | HLA 2-3 antigen-mismatched stem cell transplantation for refracotry hematologic malignancies |
Date of disclosure of the study information | 2013/10/10 |
Last modified on | 2022/10/19 17:29:57 |
HLA 2-3 antigen-mismatched stem cell transplantation for refracotry hematologic malignancies
Haploidentical stem cell transplantation for hematologic malignancies
HLA 2-3 antigen-mismatched stem cell transplantation for refracotry hematologic malignancies
Haploidentical stem cell transplantation for hematologic malignancies
Japan |
refractory hematologic malignancies
Hematology and clinical oncology |
Malignancy
NO
To investigate safety and efficacy of HLA haploidentical stem cell trnasplantation for refractory hematologic malignancies
Safety,Efficacy
Survival rate at 100 days after transplantation
Interventional
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
1
Treatment
Medicine |
fludarabine 30mg/m2 day -11,-10,-9,-8,-7,-6
melphalan 70mg/m2 day -7,-6
(cytarabine 2g/m2 day -11,-10,-9,-8)
TBI 3Gy day -5
ATG 0.5mg/kg day -3
ATG 1mg/kg day -2,-1
16 | years-old | <= |
65 | years-old | >= |
Male and Female
1) Relapse after allogeneic transplantation
2) Lack an avavilable HLA identical or 1 antigen-mismatched related or unrelated donor
1) With uncontrol diabetes
2) With uncontrol hypertension
3) With active cancer
4) Positive of HBs Ag or HBe Ag
5) Positive of HIV Ab
25
1st name | Shingo |
Middle name | |
Last name | Yano |
Jikei University Hospital
Clinical Oncology and Hematology
105-8461
3-25-8 Nishi Shinbashi Minatoku Tokyo Japan
03-3433-1111
yano@jikei.ac.jp
1st name | Shingo |
Middle name | |
Last name | Yano |
Jikei Universtiy Hospital
Clinical Oncology and Hematology
105-8461
3-25-8 Nishi Shinbashi Minatoku Tokyo Japan
03-3433-1111
yano@jikei.ac.jp
Jikei University School of Medicine
Jikei University School of Medicne
Self funding
Jikei University Ethics Committee
3-25-8 Nishi-Shinbashi Minato-ku
03-3433-1111
rinri@jikei.ac.jp
NO
2013 | Year | 10 | Month | 10 | Day |
Unpublished
Enrolling by invitation
2013 | Year | 04 | Month | 01 | Day |
2013 | Year | 09 | Month | 01 | Day |
2013 | Year | 09 | Month | 01 | Day |
2023 | Year | 10 | Month | 30 | Day |
2013 | Year | 10 | Month | 07 | Day |
2022 | Year | 10 | Month | 19 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000013069
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