Unique ID issued by UMIN | UMIN000011213 |
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Receipt number | R000013142 |
Scientific Title | Effects of low dose tolvaptan in old myocardial infarction patients with congestive heart failure |
Date of disclosure of the study information | 2013/07/18 |
Last modified on | 2015/05/13 10:59:49 |
Effects of low dose tolvaptan in old myocardial infarction patients with congestive heart failure
Effects of low dose tolvaptan in old myocardial infarction patients with congestive heart failure
Effects of low dose tolvaptan in old myocardial infarction patients with congestive heart failure
Effects of low dose tolvaptan in old myocardial infarction patients with congestive heart failure
Japan |
Old myocardial infarction patients with congestive heart failure
Cardiology |
Others
NO
To evaluate the effectiveness of long administration of low dose tolvaptan for suppressing myocardial remodeling in old myocardial infarction patients with congestive heart failure.
Efficacy
Left ventricular ejection fraction(LVEF)
NYHA class, body weight, congestive findings(leg edema, jugular vein dilatation, pulmonary congestion ), serum sodium, serum potassium, diastolic function
Interventional
Parallel
Randomized
Individual
Open -but assessor(s) are blinded
Active
2
Treatment
Medicine |
administration of tolvaptan 3.75mg/day
non-administration of tolvaptan
20 | years-old | <= |
90 | years-old | > |
Male and Female
1) Old myocardial infarction patients with congestive
heart failure
2) EF < 50%
3) Physical findings of congestion
4) No significant stenosis in coronary arteries
1) Patients with severe hypotention or cardioganic shock
2) Patients with cardiac assist device
3) Patients on hemodialysis
4) Patients with systolic blood pressure < 90mmHg
5) Patients with serum Na > 147 mEq/L or serum K > 5.5
mEq/L or T- bilirubin > 3.0 mg/dL
6) Patients considered not eligible for the study by the
attending doctor due to other reasons
200
1st name | |
Middle name | |
Last name | Minoru Yoshiyama |
Osaka city university graduate school of medicine
Department of cardiovascular medicine
1-4-3, Asahimachi Abeno-ku, Osaka
06-6645-3801
1st name | |
Middle name | |
Last name | Akihisa Hanatani |
Osaka city university graduate school of medicine
Department of cardiovascular medicine
Department of cardiovascular medicine
Osaka city university graduate school of medicine
Department of cardiovascular medicine
Osaka city university graduate school of medicine
Self funding
NO
2013 | Year | 07 | Month | 18 | Day |
Unpublished
Terminated
2013 | Year | 05 | Month | 28 | Day |
2013 | Year | 07 | Month | 01 | Day |
2013 | Year | 07 | Month | 17 | Day |
2015 | Year | 05 | Month | 13 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000013142
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