Unique ID issued by UMIN | UMIN000011341 |
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Receipt number | R000013287 |
Scientific Title | A prospective observational study on the prognosis of intracranial arterial stenotic disease |
Date of disclosure of the study information | 2013/08/01 |
Last modified on | 2015/08/14 15:06:06 |
A prospective observational study on the prognosis of intracranial arterial stenotic disease
intracranial artery Stenosis after a NAtural course in Kyoto arEa
(iSNAKE)
A prospective observational study on the prognosis of intracranial arterial stenotic disease
intracranial artery Stenosis after a NAtural course in Kyoto arEa
(iSNAKE)
Japan |
intracranial arterial stenosis
Neurology | Neurosurgery |
Others
NO
Consider the progression of the disease, the incidence of cardiovascular events, and its influencing factors exploratory on the basis of the natural course and the treatment outcome (medical treatments and endovascular treatments) of patients with symptomatic or asymptomatic intracranial arterial stenosis.
Others
none
Exploratory
Pragmatic
Not applicable
1. 3-year incidence of progression or regression of the intracranial stenotic region
2. Occurrence of ischemic stroke in a 3-year follow-up
1. Occurrence of cardiovascular events (stroke, myocardial infarction, other cardiovascular events, and vasucular death) in a 3-year follow-up
2. Occurrence of all bleeding events in a 3-year follow-up
3. Occurrence of all-causes deaths in a 3-year follow-up
4. Analysis of risk factors for progression of stenotic region
5. Analysis of risk factors for stroke and cardiovascular events
6. Occurrence of development of new stenotic lesion and analysis of its risk factors
Observational
Not applicable |
Not applicable |
Male and Female
Patients with intracranial atherosclerotic stenotic lesions (%DS>=50%) in the intracranial main arteries confirmed by MR angiographic findings.
The target vascular lesions are as follows.
1. Internal carotid artery
2. Middle cerebral artery
3. Anterior cerebral artery
4. Posterior cerebral artery
5. Intracranial vertebral artery
6. Basilar artery
Case of internal medicine treatments
1. Patients with cardiogenic brain embolism
2. Whom scheduled for reconstructive surgery or endovascular treatment
3. Patients with non-atherosclerotic stenosis (artery dissection, moyamoya disease)
4. Whom considered to be difficult to follow up due to serious complications, such as brain tumor
5. Who are scheduled to remove and will be difficult to follow up
6. Who did not consent
Case of endovascular treatments
1. Patients with cardiogenic brain embolism
2. Patients with non-atherosclerotic stenosis (artery dissection, moyamoya disease)
3. Whom considered to be difficult to follow up due to serious complications, such as brain tumor
4. Who are scheduled to remove and will be difficult to follow up
5. Who did not consent
300
1st name | |
Middle name | |
Last name | Tetsuya Tsukahara |
National Hospital Organization, Kyoto Medical Center
Department of Neurosurgery
1-1Mukaihata-cho,Fukakusa,Fushimi-ku,Kyoto 612-8555 Japan
075-641-9173
ttsukaha@kyotolan.hosp.go.jp
1st name | |
Middle name | |
Last name | Tetsuya Tsukahara |
National Hospital Organization, Kyoto
Department of Neurosurgery
1-1Mukaihata-cho,Fukakusa,Fushimi-ku,Kyoto 612-8555 Japan
075-641-9173
ttsukaha@kyotolan.hosp.go.jp
National Hospital Organization, Kyoto
Medical Center
None
Self funding
None
1. Japanense Red Cross Kyoto Daini Hospital
2. Nantan General Hospital
3. National Hospital Organization, Maizuru Medical Center
None
NO
国立病院機構京都医療センター(京都府)
京都第二赤十字病院(京都府)
公立南丹病院(京都府)
国立病院機構舞鶴医療センター(京都府)
2013 | Year | 08 | Month | 01 | Day |
Unpublished
Open public recruiting
2012 | Year | 10 | Month | 01 | Day |
2012 | Year | 10 | Month | 01 | Day |
2014 | Year | 09 | Month | 30 | Day |
prospective cohort study (one arm)
2013 | Year | 08 | Month | 01 | Day |
2015 | Year | 08 | Month | 14 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000013287
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