Unique ID issued by UMIN | UMIN000011525 |
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Receipt number | R000013482 |
Scientific Title | Identification of urinary biomarkers in diabetic nephropathy by glycan profiling |
Date of disclosure of the study information | 2013/08/20 |
Last modified on | 2023/03/05 13:12:57 |
Identification of urinary biomarkers in diabetic nephropathy by glycan profiling
U-CARE study (Urinary biomarker for continuous and rapid progression of diabetic nephropathy)
Identification of urinary biomarkers in diabetic nephropathy by glycan profiling
U-CARE study (Urinary biomarker for continuous and rapid progression of diabetic nephropathy)
Japan |
Diabetic nephropathy
Medicine in general | Cardiology | Endocrinology and Metabolism |
Nephrology | Neurology |
Others
YES
Identification of urinary biomarkers to predict the progression of diabetic nephropathy by lectin array analyses
Others
To evaluate the predictive values of urinary markers identified by lectin array analyses
Exploratory
Others
Not applicable
Decline of estimated glomerular filtration rate (eGFR)
Increase in albuminuria.
Observational
20 | years-old | <= |
80 | years-old | > |
Male and Female
The patients with type 1 and type diabetes.
The patients with new onset of malignancies within 5 years. Liver cirrhosis.
800
1st name | Jun |
Middle name | |
Last name | Wada |
Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Department of Medicine and Clinical Science
700-8558
2-5-1 Shikata-cho, Kita-ku, Okayama 700-8558, Japan
086-235-7235
junwada@okayama-u.ac.jp
1st name | Koki |
Middle name | |
Last name | Mise |
Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Department of Medicine and Clinical Science
700-8558
2-5-1 Shikata-cho, Kita-ku, Okayama 700-8558, Japan
0862357232
kokims-frz@okayama-u.ac.jp
Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Health Labor Sciences Research Grant, Japan
Japanese Governmental office
Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences and Okayama University Hospital, Ethics Committee
2-5-1 Shikata-cho, Kita-ku, Okayama 700-8558, Japan
086-235-6503
mae6605@adm.okayama-u.ac.jp
NO
2013 | Year | 08 | Month | 20 | Day |
Unpublished
777
No longer recruiting
2012 | Year | 06 | Month | 26 | Day |
2012 | Year | 06 | Month | 26 | Day |
2012 | Year | 06 | Month | 26 | Day |
2028 | Year | 03 | Month | 31 | Day |
We will perform the lectin array analyses to identify urinary markers to predict the progression of diabetic nephropathy, i.e. decline of eGFR and increase in albuminuria. We plan to measure the levels ofurinary markers by ELISA, such as Haptoglobin, Alpha-2-macroglobulin, Apolipoprotein A-I, Protein AMBP (alpha-1-microglobulin), Hemopexin, Ceruloplasmin, Alpha-1B-glycoprotein, Prostaglandin-H2 D-isomerase, Alpha-1-acid glycoprotein 1 (orosomucoid), Vitamin D-binding protein, N-acetylmuramoyl-L-alanine amidase, Alpha-2-HS-glycoprotein (Fetuin-A), Angiotensinogen, Kininogen-1, Complement C4-A, Plasma protease C1 inhibitor, Complement C3, Antithrombin-III, Prothrombin.
2013 | Year | 08 | Month | 20 | Day |
2023 | Year | 03 | Month | 05 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000013482
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