Unique ID issued by UMIN | UMIN000011951 |
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Receipt number | R000013958 |
Scientific Title | Effect of epigallocatechin supplementation on the immune response to influenza vaccination |
Date of disclosure of the study information | 2013/10/08 |
Last modified on | 2015/07/08 11:15:28 |
Effect of epigallocatechin supplementation on the immune response to influenza vaccination
Epigallocatechin and immune response to influenza vaccination
Effect of epigallocatechin supplementation on the immune response to influenza vaccination
Epigallocatechin and immune response to influenza vaccination
Japan |
Influenza infection
Infectious disease |
Others
NO
To investigate whether epigallocatechin supplementation augment the immune response to influenza vaccination
Safety,Efficacy
Confirmatory
Explanatory
Not applicable
Rate of influenza-infection symptoms and antibody titer to influenza after the influenza vaccination
The extent of cytokine production by lymphocyte fraction after antigen stimulation by ELISPOT method
Interventional
Parallel
Randomized
Individual
Double blind -all involved are blinded
Placebo
YES
NO
Institution is considered as a block.
YES
No need to know
6
Prevention
Food |
Supplementation of EGC (3.0 mg/dL) for 4 months in subjects <65 years.
Supplementation of EGC (1.5 mg/dL) for 4 months in subjects <65 years.
Supplementation of placebo tea for 4 months in subjects <65 years.
Supplementation of EGC (3.0 mg/dL) for 4 months in subjects ≥70 years.
Supplementation of EGC (1.5 mg/dL) for 4 months in subjects ≥70 years.
Supplementation of placebo tea for 4 months in subjects ≥70 years.
20 | years-old | <= |
Not applicable |
Male and Female
Subjects who are recruited in the Osaka Medical College (n=90) and subjects in the Aiwa geriatric health services facilities (n=90).
Subjects who are in the bad health condition, those who cannot safely ingest EGC-containing Tea, and those who are taking corticosteroid or other immuno-suppressive agents will be excluded from the study.
180
1st name | |
Middle name | |
Last name | Nobukazu Ishizaka |
Osaka Medical College
Internal Medicine3
Daigaku-machi2-7 Takatsuki-shi Osaka Japan
072-683-1221
omc3nai-group@umin.ac.jp
1st name | |
Middle name | |
Last name | Koichi Sohmiya |
Osaka Medical College
Internal Medicine3
Daigaku-machi2-7 Takatsuki-shi Osaka Japan
072-683-1221
omc3nai-group@umin.ac.jp
Osaka Medical College
Agriculture-Medicine cooperation project
Japan
None
None
NO
大阪医科大学附属病院(大阪)、豊中愛和会(大阪)
2013 | Year | 10 | Month | 08 | Day |
Partially published
This study did not shown that epigallocatechin tea could activate immune function after influenza vaccination.
Completed
2013 | Year | 07 | Month | 01 | Day |
2013 | Year | 09 | Month | 01 | Day |
2014 | Year | 02 | Month | 28 | Day |
2014 | Year | 03 | Month | 31 | Day |
2014 | Year | 03 | Month | 31 | Day |
2016 | Year | 07 | Month | 31 | Day |
2013 | Year | 10 | Month | 03 | Day |
2015 | Year | 07 | Month | 08 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000013958
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