Unique ID issued by UMIN | UMIN000012156 |
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Receipt number | R000014211 |
Scientific Title | Involvement of iron-evoked oxidative stress in smoking-related endothelial dysfunction in healthy young men |
Date of disclosure of the study information | 2013/10/29 |
Last modified on | 2013/10/29 13:45:21 |
Involvement of iron-evoked oxidative stress in smoking-related endothelial dysfunction in healthy young men
Iron and endothelial dysfunction
Involvement of iron-evoked oxidative stress in smoking-related endothelial dysfunction in healthy young men
Iron and endothelial dysfunction
Japan |
young male smoker and non-smoker
Medicine in general | Cardiology |
Others
NO
We examine whether (1) intravenous iron infusion impaire endothelial function evaluated by flow-mediated vasodilatation (FMD) in non-smokers and (2) deferoxamine, a potent iron chelator, ameliorat endothelial dysfunction in healthy smokers.
Efficacy
Improvement of endothelial function
Interventional
Parallel
Non-randomized
Open -no one is blinded
Active
2
Treatment
Medicine |
saccharated ferric oxide/5% glucose solution
deferoxamine mesylate/0.9%saline solution
20 | years-old | <= |
35 | years-old | > |
Male
smoker n=10
non-smoker n=10
Under 20years old
Women
subjects who have already had disease
40
1st name | |
Middle name | |
Last name | Kei Fukami |
Kurume University School of Medicine
Department of Medicine, Division of Nephrology
67 Asahi-machi Kurume city, Fukuoka
0942-31-7002
fukami@med.kurume-u.ac.jp
1st name | |
Middle name | |
Last name | Kei Fukami |
Kurume University School of Medicine
Department of Medicine, Division of Nephrology
67 Asahi-machi Kurume city, Fukuoka
0942-31-7002
fukami@med.kurume-u.ac.jp
Kurume University School of Medicine
Internal Medicine III, Kurume University School of Medicine
Other
NO
2013 | Year | 10 | Month | 29 | Day |
Unpublished
Completed
1998 | Year | 10 | Month | 06 | Day |
1998 | Year | 11 | Month | 01 | Day |
2013 | Year | 10 | Month | 29 | Day |
2013 | Year | 10 | Month | 29 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000014211
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