Unique ID issued by UMIN | UMIN000012218 |
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Receipt number | R000014287 |
Scientific Title | A phase I study of conbination therapy with intratumorak administration of dendritic cells and radiation for far advanced esophageal cancer |
Date of disclosure of the study information | 2013/11/05 |
Last modified on | 2013/11/05 19:06:24 |
A phase I study of conbination therapy with intratumorak administration of dendritic cells and radiation for far advanced esophageal cancer
Chiba RT-DC therapy
A phase I study of conbination therapy with intratumorak administration of dendritic cells and radiation for far advanced esophageal cancer
Chiba RT-DC therapy
Japan |
Esophageal cancer
Gastrointestinal surgery |
Malignancy
NO
Evaluation of safety of combination therapy with intratumoral administration of dendritic cells and radiation for far-advanced esophageal cancer
Safety
Evaluation of safety
Tumor response,
Evalustion of immunoresponse
Interventional
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
1
Treatment
Medicine | Vaccine | Maneuver |
Other |
Radition
Dendritic cells
20 | years-old | <= |
75 | years-old | > |
Male and Female
1.Histrogically proven esophageal squamous cell carcinoma
2.Standard-treatment-failured cases
3.Measurable cases to which no radiation is administered
4.age 20 and more, 74 and less
5.PS0-1
6.4 weeks of more has been past after prior treatment
7. 2 months or more of survival can be estimated
8. Adequate organ functions
9. Written informed consent
1. History of radiotherapy or immunotherapy
2. tumor has fistula
3. obvious infection
4. hypoalbuminemia
5. uncontrorable pleural effusion or ascites
6. severe heart failure
7. other complications (ileus, pneumonitis, pleural fibrosis, DM, renal failure, liver cirrhosis)
8. Psychologic diorders
9. double cancers
10. steroid administration
6
1st name | |
Middle name | |
Last name | Hisahiro Matsubara |
Chiba University
Department of Frontier surgery
1-8-1, Inohana, Chuoku, Chiba
043-226-2110
matsuhm@faculty.chiba-u.jp
1st name | |
Middle name | |
Last name | Yasunori Akutsu |
Chiba University
Department of Frontier Surgery
1-8-1, Inohana, Chuoku, Chiba
043-226-2110
yakutsu@faculty.chiba-u.jp
Chiba University
Chiba University Hospital
Self funding
NO
2013 | Year | 11 | Month | 05 | Day |
Unpublished
Open public recruiting
2011 | Year | 07 | Month | 27 | Day |
2013 | Year | 11 | Month | 05 | Day |
2013 | Year | 11 | Month | 05 | Day |
2013 | Year | 11 | Month | 05 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000014287
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