UMIN-CTR Clinical Trial

Unique ID issued by UMIN UMIN000012333
Receipt number R000014421
Scientific Title Expression and functional analyses of immunoreceptors on human blood cells
Date of disclosure of the study information 2014/01/15
Last modified on 2023/02/24 14:22:47

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Basic information

Public title

Expression and functional analyses of immunoreceptors on human blood cells

Acronym

Functional analyses of human immunoreceptors

Scientific Title

Expression and functional analyses of immunoreceptors on human blood cells

Scientific Title:Acronym

Functional analyses of human immunoreceptors

Region

Japan


Condition

Condition

none

Classification by specialty

Adult

Classification by malignancy

Others

Genomic information

YES


Objectives

Narrative objectives1

1. To elucidate protein and gene expression of immunoreceptors on human blood cells.
2. To clarify the function of immunoreceptors by utilizing human primary blood cells and estimate the homology of the receptors between human and mouse.
3. To identify a novel immunoreceptor.

Basic objectives2

Others

Basic objectives -Others

molecular biology, Basic research

Trial characteristics_1


Trial characteristics_2


Developmental phase



Assessment

Primary outcomes

Expression and function of immunoreceptors on human blood cells. Identification of a novel immunoreceptor.

Key secondary outcomes



Base

Study type

Observational


Study design

Basic design


Randomization


Randomization unit


Blinding


Control


Stratification


Dynamic allocation


Institution consideration


Blocking


Concealment



Intervention

No. of arms


Purpose of intervention


Type of intervention


Interventions/Control_1


Interventions/Control_2


Interventions/Control_3


Interventions/Control_4


Interventions/Control_5


Interventions/Control_6


Interventions/Control_7


Interventions/Control_8


Interventions/Control_9


Interventions/Control_10



Eligibility

Age-lower limit

20 years-old <=

Age-upper limit


Not applicable

Gender

Male and Female

Key inclusion criteria

Healthy

Key exclusion criteria

Unwilling to apply the study

Target sample size

300


Research contact person

Name of lead principal investigator

1st name
Middle name
Last name Akira Shibuya

Organization

University of Tsukuba

Division name

Department of Immunology, Division of Biomedical Science, Faculty of Medicine

Zip code


Address

1-1-1 Tennodai, Tsukuba Science-City, 305-8575, Japan

TEL

029-853-3281

Email

ashibuya@md.tsukuba.ac.jp


Public contact

Name of contact person

1st name
Middle name
Last name Satoko Tahara

Organization

University of Tsukuba

Division name

Department of Immunology, Division of Biomedical Science, Faculty of Medicine

Zip code


Address

1-1-1 Tennodai, Tsukuba Science-City, 305-8575, Japan

TEL

029-853-3281

Homepage URL


Email

tokothr@md.tsukuba.ac.jp


Sponsor or person

Institute

University of Tsukuba

Institute

Department

Personal name



Funding Source

Organization

Create revolutionary technological seeds for science and technology innovation (CREST), Japan science and technology agency (JST)

Organization

Division

Category of Funding Organization

Japanese Governmental office

Nationality of Funding Organization



Other related organizations

Co-sponsor


Name of secondary funder(s)



IRB Contact (For public release)

Organization


Address


Tel


Email



Secondary IDs

Secondary IDs

NO

Study ID_1


Org. issuing International ID_1


Study ID_2


Org. issuing International ID_2


IND to MHLW



Institutions

Institutions



Other administrative information

Date of disclosure of the study information

2014 Year 01 Month 15 Day


Related information

URL releasing protocol


Publication of results

Unpublished


Result

URL related to results and publications


Number of participants that the trial has enrolled


Results


Results date posted


Results Delayed


Results Delay Reason


Date of the first journal publication of results


Baseline Characteristics


Participant flow


Adverse events


Outcome measures


Plan to share IPD


IPD sharing Plan description



Progress

Recruitment status

Completed

Date of protocol fixation

2013 Year 11 Month 15 Day

Date of IRB

2013 Year 11 Month 15 Day

Anticipated trial start date

2014 Year 01 Month 16 Day

Last follow-up date

2023 Year 02 Month 22 Day

Date of closure to data entry


Date trial data considered complete


Date analysis concluded



Other

Other related information

We will analyze the expression and function of immunoreceptors by ELISA, FACS, WB, qPCR, and gene sequence method. We will also identify a novel immunoreceptor by gene cloning technics.


Management information

Registered date

2013 Year 11 Month 18 Day

Last modified on

2023 Year 02 Month 24 Day



Link to view the page

Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000014421


Research Plan
Registered date File name

Research case data specifications
Registered date File name

Research case data
Registered date File name