Unique ID issued by UMIN | UMIN000012487 |
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Receipt number | R000014618 |
Scientific Title | Combination therapy of losartan plus hydrochlorothiazide versus any angiotensin II blocker plus any calcium antagonist: effects on blood pressure and cardiac function |
Date of disclosure of the study information | 2014/01/01 |
Last modified on | 2013/12/04 15:19:30 |
Combination therapy of losartan plus hydrochlorothiazide versus any angiotensin II blocker plus any calcium antagonist: effects on blood pressure and cardiac function
Effects of losartan plus hydrochlorothiazide versus angiotensin II blocker plus calcium antagonist on blood pressure
Combination therapy of losartan plus hydrochlorothiazide versus any angiotensin II blocker plus any calcium antagonist: effects on blood pressure and cardiac function
Effects of losartan plus hydrochlorothiazide versus angiotensin II blocker plus calcium antagonist on blood pressure
Japan |
Essential hypertension
Not applicable |
Others
NO
To investigate effects of combination therapy of losartan plus hydrochlorothiazide versus angiotensin II blocker plus calcium antagonist on blood pressure and cardiac function in hypertensive patients
Efficacy
Exploratory
Pragmatic
Not applicable
Blood lowering effect
Cardiac protective effect
Parallel
Randomized
Open -no one is blinded
Active
2
Treatment
Medicine |
Patents receiving losartan plus hydrochlorothiazide
Patents receiving angiotensin II blocker plus calcium antagonist
20 | years-old | <= |
Not applicable |
Male and Female
Patients in whom their blood pressures are not controlled within target blood pressure levels under a normal dose of angiotensin II blocker
(1) ischemic heart disease
(2) ischemic celebrovascular disease
(3) serum creatinine >1.5 mg/dl and more(4) HbA1c <8.0 mg/dl and more
(5) not tolerated to a new drug
(6) patients already given high dose therapy of angiotensin II blocker
26
1st name | |
Middle name | |
Last name | Nobukazu Ishizaka |
Osaka Medical College
Department of Cardiology
2-7, Daigaku-machi, Takatsuki, Osaka
072-683-1221
Ishizaka@poh.osaka-med.ac.jp
1st name | |
Middle name | |
Last name | Takahide Ito |
Osaka Medical College
Department of Cardiology
2-7, Daigaku-machi, Takatsuki, Osaka
072-683-1221
in3016@poh.osaka-med.ac.jp
Department of Cardiology, Osaka Medical College
Department of Cardiology, Osaka Medical College
Self funding
NO
2014 | Year | 01 | Month | 01 | Day |
Unpublished
Terminated
2011 | Year | 05 | Month | 02 | Day |
2011 | Year | 05 | Month | 02 | Day |
2012 | Year | 06 | Month | 30 | Day |
2013 | Year | 12 | Month | 04 | Day |
2013 | Year | 12 | Month | 04 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000014618
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