Unique ID issued by UMIN | UMIN000012539 |
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Receipt number | R000014668 |
Scientific Title | The Role of Presepsin and Other Markers in Early Diagnosis and Evaluation of Treatment of Pediatric Bacterial Infections. |
Date of disclosure of the study information | 2013/12/15 |
Last modified on | 2014/08/17 18:04:04 |
The Role of Presepsin and Other Markers in Early Diagnosis and Evaluation of Treatment of Pediatric Bacterial Infections.
The Role of Presepsin and Other Markers in Early Diagnosis and Evaluation of Treatment of Pediatric Bacterial Infections.
The Role of Presepsin and Other Markers in Early Diagnosis and Evaluation of Treatment of Pediatric Bacterial Infections.
The Role of Presepsin and Other Markers in Early Diagnosis and Evaluation of Treatment of Pediatric Bacterial Infections.
Japan |
bacterial infection
Pediatrics | Laboratory medicine | Emergency medicine |
Intensive care medicine |
Others
NO
Study 1. To evaluate the efficacy of presepsin in the diagnosis and assessment of pediatric bacterial infection in the emergency department and pediatric outpatient clinic.
Study 2. To evaluate the relationship between presepsin and inflammatory markers in serious pediatric bacterial infections.
Efficacy
Study 1. To evaluate the cut-off value of presepsin in the diagnosis and assessment of pediatric bacterial infections.
Study 2. To evaluate the correlation between clinical symptoms and white-blood cell count, absolute neutrophil count, C-reactive protein, procalcitonin, Interleukin 6 and presepsin levels.
Interventional
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
1
Diagnosis
Maneuver |
Additional 1.5 ml of blood sample will be withdrawn to analyze presepsin and other markers at the routine blood examination.
Not applicable |
16 | years-old | > |
Male and Female
Feverish patients need blood analysis to rule out bacterial infections in the pediatric emergency division and pediatric outpatient clinic.
Fever is defined as the presence of an axillary temperature >=38 degree C.
Serious bacterial infection is defined as the presence of bacteremia, urinary tract infection, pneumonia, meningitis, osteomyelitis, septic arthritis and/or sepsis.
All patients or their guardians are required to sign a consent form.
Patients who have 1) received antibiotic treatment within 48 hours , 2) a fever caused by vaccination, 3) had surgery within 7 days , and 4) a fever lasting longer than 3 days before admission and patients considered ineligible for this study.
100
1st name | |
Middle name | |
Last name | Akira Takasu |
Faculty of Medicine, Osaka Medical College
Department of Emergency Medicine
2-7 Daigaku-machi, Takatsuki City, Osaka
072-683-1221
takasu@poh.osaka-med.ac.jp
1st name | |
Middle name | |
Last name | Masahiko Nitta |
Faculty of Medicine, Osaka Medical College
Department of Emergency Medicine
2-7 Daigaku-machi, Takatsuki City, Osaka
072-683-1221
nittam@poh.osaka-med.ac.jp
Faculty of Medicine, Osaka Medical College
None
Self funding
NO
2013 | Year | 12 | Month | 15 | Day |
Unpublished
Enrolling by invitation
2013 | Year | 12 | Month | 27 | Day |
2014 | Year | 04 | Month | 01 | Day |
2013 | Year | 12 | Month | 10 | Day |
2014 | Year | 08 | Month | 17 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000014668
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