Unique ID issued by UMIN | UMIN000012735 |
---|---|
Receipt number | R000014880 |
Scientific Title | Effects of sitagliptin on daily glucose fluctuation in Japanese type 2 diabetic outpatients inadequately controlled with insulin therapy |
Date of disclosure of the study information | 2013/12/31 |
Last modified on | 2014/12/09 14:20:29 |
Effects of sitagliptin on daily glucose fluctuation in Japanese type 2 diabetic outpatients inadequately controlled with insulin therapy
Effects of sitagliptin on daily glucose fluctuation in Japanese type 2 diabetic outpatients inadequately controlled with insulin therapy
Effects of sitagliptin on daily glucose fluctuation in Japanese type 2 diabetic outpatients inadequately controlled with insulin therapy
Effects of sitagliptin on daily glucose fluctuation in Japanese type 2 diabetic outpatients inadequately controlled with insulin therapy
Japan |
type 2 diabetes
Endocrinology and Metabolism |
Others
NO
To investigate the effects of sitagliptin on daily glucose fluctuation in Japanese type 2 diabetes outpatients inadequately controlled with insulin therapy by using CGM. And we investigate the effects of sitagliptin on oxidative stress.And also, we investigate the effects of CGM on their feeling of distress by using PAID scale.
Efficacy
the change of daily glucose fluctuation (MAGE, SD) and oxidative stress (8-iso PGF2)
the change of HbA1c, fasting plasma glucose level, 1,5-AG, hs-CRP, incidence of hypoglycemia and feeling of distress.
Observational
20 | years-old | <= |
Not applicable |
Male and Female
1)HbA1c value is between 6.5% and 8.4%.
2)Type 2 diabetic outpatients medicated with insulin therapy for more than 6 months.
1)Type 1 diabetic patients.
2)Patients with severe renal failure.
3)Patients medicated with DPP-4 inhibitor or GLP-1 receptor agonist before start of this study.
4)Patients who are pregnant or in lactation period.
5)Juged as ineligible by clinical investigators.
30
1st name | |
Middle name | |
Last name | Jiro Nakamura |
Aichi Medical University
Division of Diabetes, Department of Internal Medicine, Diabetes Center
1-1 Yazakokarimata, Nagakute, Aichi
0561-63-1683
jiro@aichi-med-u.ac.jp
1st name | |
Middle name | |
Last name | Yoshiro Kato |
Aichi Medical University
Division of Diabetes, Department of Internal Medicine, Diabetes Center
1-1 Yazakokarimata, Nagakute, Aichi
0561-63-1683
ykato4@aichi-med-u.ac.jp
Aichi Medical University
Division of Diabetes, Department of Internal Medicine, Diabetes Center
Aichi Medical University
Division of Diabetes, Department of Internal Medicine, Diabetes Center
Self funding
NO
愛知医科大学医学部
内科学講座糖尿病内科/糖尿病センター
2013 | Year | 12 | Month | 31 | Day |
Unpublished
Completed
2012 | Year | 08 | Month | 01 | Day |
2012 | Year | 08 | Month | 01 | Day |
prospective study, case series study
2013 | Year | 12 | Month | 31 | Day |
2014 | Year | 12 | Month | 09 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000014880
Research Plan | |
---|---|
Registered date | File name |
Research case data specifications | |
---|---|
Registered date | File name |
Research case data | |
---|---|
Registered date | File name |