Unique ID issued by UMIN | UMIN000012795 |
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Receipt number | R000014944 |
Scientific Title | Effects of Tulobuterol Patch (Long acting beta-2 agonist) on dyspnea during exercise in patients with COPD |
Date of disclosure of the study information | 2014/01/08 |
Last modified on | 2014/01/08 20:57:50 |
Effects of Tulobuterol Patch (Long acting beta-2 agonist) on dyspnea during exercise in patients with COPD
Effects of Tulobuterol Patch in COPD
Effects of Tulobuterol Patch (Long acting beta-2 agonist) on dyspnea during exercise in patients with COPD
Effects of Tulobuterol Patch in COPD
Japan |
Chronic obstructive pulmonary
disease (COPD)
Pneumology |
Others
NO
Evaluation for efficiency of tulobuterol patch on dyspnea in COPD patients during exercise
Efficacy
Confirmatory
Pragmatic
Not applicable
Improvement for dyspnea in COPD patients in diary living and exercise activities
Improvement for pulmonary function value in COPD
Interventional
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
1
Treatment
Medicine | Behavior,custom |
Tulobuterol Patch
ADL, exercise tolerance
40 | years-old | <= |
Not applicable |
Male and Female
Subjects: COPD patients
COPD was diagnosed based on the patient medical history, spirometry, and radiologic findings, including high-resolution computed tomography of the chest according to Global Initiative for Chronic Obstructive Lung Disease(GOLD) guideline.
Inclusion criteria included the presence of moderate to severe COPD, including post-bronchodilator forced expiratory volume in 1s (FEV1)/forced vital capacity (FVC) ratio of <70% and percent predicted FEV1 (%FEV1) <80%. Only patients whose condition had remained stable for >= 1 month more were eligible.
Patients with any of the following were excluded:
1)Bronchial asthma
2)Respiratory tract infection within the preceding 4 weeks
3)Respiratory failure with home oxygen therapy
4)who required oral corticosteroids
5)hypertension, heart disease, thyroid disease, diabetes, or skin disease
and patients contraindicated to beta-2 agonists
6)Pregnant
7)others contraindicated to exercise
10
1st name | |
Middle name | |
Last name | Yuzo Kodama |
Juntendo University Scool of Medicine
Respiratory Medicine
2-1-1 Hongo Bunkyoku Tokyo Japan
+81-3-5802-1063
ykodama@juntendo.ac.jp
1st name | |
Middle name | |
Last name | Yuzo Kodama |
Juntendo University Scool of Medicine
Respiratory Medicine
2-1-1 Hongo Bunkyoku Tokyo Japan
+81-3-5802-1063
ykodama@juntendo.ac.jp
Juntendo University
Faculty of Medicine and graduate
School of Medicine
Abbott Japan
Other
Japan
NO
順天堂大学医学部附属順天堂医院(東京都)
2014 | Year | 01 | Month | 08 | Day |
Unpublished
Tulobuterol patch produces significant improvement in dyspnea during exercise in stable COPD and may contribute to improve the quality of life in patients with COPD.
Completed
2011 | Year | 03 | Month | 01 | Day |
2011 | Year | 04 | Month | 01 | Day |
2013 | Year | 03 | Month | 31 | Day |
2013 | Year | 03 | Month | 31 | Day |
2013 | Year | 03 | Month | 31 | Day |
2013 | Year | 11 | Month | 01 | Day |
Pulmonary function test (spirometric indices) were not improved.
2014 | Year | 01 | Month | 08 | Day |
2014 | Year | 01 | Month | 08 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000014944
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