Unique ID issued by UMIN | UMIN000013201 |
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Receipt number | R000014968 |
Scientific Title | Phase I/II trial of nab-Paclitaxel,Carboplatin,plus Bevacizumab chemotherapy for patients with advanced Non-Squamous Non-Small Cell Lung Cancer. |
Date of disclosure of the study information | 2014/02/19 |
Last modified on | 2021/03/31 11:10:20 |
Phase I/II trial of nab-Paclitaxel,Carboplatin,plus Bevacizumab chemotherapy for patients with advanced Non-Squamous Non-Small Cell Lung Cancer.
Phase I/II trial of nab-Paclitaxel,Carboplatin,plus Bevacizumab chemotherapy for patients with advanced Non-Squamous Non-Small Cell Lung Cancer.
Phase I/II trial of nab-Paclitaxel,Carboplatin,plus Bevacizumab chemotherapy for patients with advanced Non-Squamous Non-Small Cell Lung Cancer.
Phase I/II trial of nab-Paclitaxel,Carboplatin,plus Bevacizumab chemotherapy for patients with advanced Non-Squamous Non-Small Cell Lung Cancer.
Japan |
Advanced Non-Squamous Non-Small Cell Lung Cancer
Medicine in general | Pneumology | Hematology and clinical oncology |
Malignancy
NO
To assess the safety and efficacy of nab-Paclitaxel, Carboplatin,plus Bevacizumab chemotherapy
Safety,Efficacy
Exploratory
Pragmatic
Phase I,II
PhaseI:Dose Limiting Toxicity(DLT),Minimal Tolerated Dose(MTD),Recommended Dose(RD)
PhaseII:Objective Response Rate(ORR)
PhaseI:Safety,Objective Response Rate(ORR),Progression Free Survival(PFS),Overall Survival(OS)
Interventional
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
1
Treatment
Medicine |
Nab-Paclitaxel,Carboplatin,plus Bevacizumab chemotherapy
20 | years-old | <= |
75 | years-old | > |
Male and Female
The patients histologically or cytologically diagnosed advanced Non-Squamous Non-Small Cell Lung Cancer.
ECOG Performanse status 0-1
The patients who have brain metastasis and have symptom or need therapy.
The patients who have hemoptysis.
61
1st name | |
Middle name | |
Last name | Makoto Nishio |
Cancer Institute Hospital of JFCR
Department of Thoracic Medical oncology
3-8-31 Ariake Koto-ku Tokyo Japan
03-3520-0111
mnishio@jfcr.or.jp
1st name | |
Middle name | |
Last name | Atsushi Horiike |
Cancer Institute Hospital of JFCR
Department of Thoracic Medical oncology
3-8-31 Ariake Koto-ku Tokyo Japan
03-3520-0111
atsushi.horiike@jfcr.or.jp
Cancer Institute Hospital of JFCR
Cancer Institute Hospital of JFCR
Self funding
NO
2014 | Year | 02 | Month | 19 | Day |
Unpublished
Completed
2013 | Year | 10 | Month | 16 | Day |
2014 | Year | 02 | Month | 19 | Day |
2014 | Year | 02 | Month | 10 | Day |
2017 | Year | 05 | Month | 29 | Day |
2017 | Year | 05 | Month | 29 | Day |
2014 | Year | 02 | Month | 19 | Day |
2021 | Year | 03 | Month | 31 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000014968
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