Unique ID issued by UMIN | UMIN000012947 |
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Receipt number | R000015143 |
Scientific Title | Effects of atomoxetine on cognitive functions in normal subjects using fMRI |
Date of disclosure of the study information | 2014/01/24 |
Last modified on | 2016/10/04 17:01:39 |
Effects of atomoxetine on cognitive functions in normal subjects using fMRI
Effects of atomoxetine on cognitive functions in normal subjects using fMRI
Effects of atomoxetine on cognitive functions in normal subjects using fMRI
Effects of atomoxetine on cognitive functions in normal subjects using fMRI
Japan |
Healthy adults
Adult |
Others
NO
The aim of this study is to investigate the effects of atomoxetine on human cognitive functions.
Efficacy
Comparison of BOLD signal changes measured by fMRI between placebo and atomoxetine conditions.
Interventional
Cross-over
Randomized
Individual
Single blind -participants are blinded
Placebo
2
Prevention
Medicine |
1day 1 time atomoxetine 40 mg
Washout duration 1 week
1day 1 time placebo
1day 1 time placebo
Washout duration 1 week
1day 1 time atomoxetine 40 mg
20 | years-old | <= |
40 | years-old | > |
Male and Female
Subjects with no history of psychiatric disorders.
Subjects who have the ability to provide informed consent and adhere to the protocol.
Subjects with drug allergy.
Subjects with cardiovascular disorder, glaucoma, liver and renal dysfunction, urination difficulty.
Subjects with history of pheochromocytoma, convulsive seizure, hypertension, cerebrovascular disorder, orthostatic hypotension.
Subjects taking any drug within 1 week.
Subjects with contraindications to MRI.
Subjects who are judged as not suitable for participation in this study.
25
1st name | |
Middle name | |
Last name | Hidenori Suzuki |
Nippon Medical School
Department of Pharmacology
1-1-5, Sendagi, Bunkyo-ku, Tokyo
03-3822-2131
hsuzuki@nms.ac.jp
1st name | |
Middle name | |
Last name | Yumiko Ikeda |
Nippon Medical School
Department of Pharmacology
1-1-5, Sendagi, Bunkyo-ku, Tokyo
03-3822-2131
y-ikeda@nms.ac.jp
Nippon Medical School
Ministry of Education, Culture, Sports, Science and Technology
Japanese Governmental office
NO
2014 | Year | 01 | Month | 24 | Day |
Unpublished
Suspended
2012 | Year | 12 | Month | 01 | Day |
2012 | Year | 12 | Month | 26 | Day |
2014 | Year | 01 | Month | 24 | Day |
2016 | Year | 10 | Month | 04 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000015143
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