Unique ID issued by UMIN | UMIN000014379 |
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Receipt number | R000015833 |
Scientific Title | Multicenter prospective registry of dural arteriovenous fistula without retrograde leptomeningeal venous drainage |
Date of disclosure of the study information | 2014/07/01 |
Last modified on | 2021/09/07 15:18:50 |
Multicenter prospective registry of dural arteriovenous fistula without retrograde leptomeningeal venous drainage
Multicenter prospective registry of dural arteriovenous fistula without retrograde leptomeningeal venous drainage
Multicenter prospective registry of dural arteriovenous fistula without retrograde leptomeningeal venous drainage
Multicenter prospective registry of dural arteriovenous fistula without retrograde leptomeningeal venous drainage
Japan |
dural arteriovenous fistula
Neurosurgery |
Others
NO
To ellcidate the natural course of dural arteriovenous fistula with no retrograde leptomeningeal venous drainage
Others
natural history
1) death
2) any stroke
1) any treatment intervention
2) change of Borden classification
3) any new finding on brain MRI
Observational
Not applicable |
Not applicable |
Male and Female
1) diagnosed as dural arteriovenous fistula
2) confirmed by digital subtraction angiography (DSA)
3) eligible for follow-up
none
100
1st name | Susumu |
Middle name | |
Last name | Miyamoto |
Kyoto University, Graduate School of Medicine
Department of Neurosurgery
606-8507
Kawahara-cho 54, Syogoin, Sakyo-ku, Kyoto-city
075-751-3459
miy@kuhp.kyoto-u.ac.jp
1st name | Akira |
Middle name | |
Last name | Ishii |
Kyoto University, Graduate School of Medicine
Department of Neurosurgery
606-8507
Kawahara-cho 54, Syogoin, Sakyo-ku, Kyoto-city
075-751-3459
dural@kuhp.kyoto-u.ac.jp
Kyoto University
Japanese Society for Neuroendovascular Therapy
Non profit foundation
Kyoto University Graduate School and Faculty of Medicine, Ethics committee
Yoshida-Konoe-cho, Sakyo-ku, Kyoto 606-8501, JAPAN
075-753-4680
ethcom@kuhp.kyoto-u.ac.jp
NO
京都大学(京都府)、城山病院(大阪府)、神戸市立医療センター中央市民病院(兵庫県)、神鋼病院(兵庫県)、横浜新都市脳神経外科病院(神奈川県)、小倉記念病院(福岡県)、松下記念病院(大阪府)、赤穂市民病院(兵庫県)、滋賀県立成人病センター(滋賀県)、倉敷中央病院(岡山県)、京都医療センター(京都府)、康生会武田病院(京都府)、高松赤十字病院(香川県)、高知医療センター(高知県)、福井赤十字病院(福井県)、国立循環器病研究センター(大阪府)、市立長浜病院(滋賀県)
2014 | Year | 07 | Month | 01 | Day |
NA
Published
NA
110
No patient had conversion to higher type of Borden classification or intracranial hemorrhage during the follow-up. Five patients showed spontaneous improvement of neurological symptoms (5/28, 17.9%), and 5 patients showed a spontaneous decrease of shunt flow on imaging during follow-up (17.9%). The stenosis or occlusion of the draining sinuses at initial angiography was significantly associated with the shunt flow reduction during the follow-up (p=0.02).
2021 | Year | 06 | Month | 30 | Day |
From April 2013 to March 2016, consecutive patients with DAVF were screened at 13 study institutions. 110 patients with intracranial DAVF were screened and 28 patients with Borden type I DAVF were prospectively followed.
We collected data on baseline characteristics, clinical symptoms, angiography, and neuroimaging. Patients with Borden type I DAVF received conservative care while palliative intervention was considered when the neurological symptoms were intolerable, and were followed at 6, 12, 24, and 36 months after inclusion.
None due to the observational nature of the present study.
deterioration of the neurological symptoms, MRI at 6, 12, 24, and 36 months after enrollment.
Main results already published
2013 | Year | 04 | Month | 01 | Day |
2013 | Year | 03 | Month | 25 | Day |
2013 | Year | 10 | Month | 01 | Day |
2018 | Year | 12 | Month | 31 | Day |
Primary outcome
any death, any stroke
Secondary outcome
1) Surgical intervention
2) change of Borden type
3) new findings on brain MRI
2014 | Year | 06 | Month | 26 | Day |
2021 | Year | 09 | Month | 07 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000015833
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