Unique ID issued by UMIN | UMIN000014399 |
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Receipt number | R000016547 |
Scientific Title | Evaluation of infectious disease consultations with a rapid microbiological identification system (Verigene system) for Gram-positive and Gram-negative bacteremia |
Date of disclosure of the study information | 2014/06/29 |
Last modified on | 2016/06/27 09:49:57 |
Evaluation of infectious disease consultations with a rapid microbiological identification system (Verigene system) for Gram-positive and Gram-negative bacteremia
Evaluation of infectious disease consultations with a rapid microbiological identification system (Verigene system) for Gram-positive and Gram-negative bacteremia
Evaluation of infectious disease consultations with a rapid microbiological identification system (Verigene system) for Gram-positive and Gram-negative bacteremia
Evaluation of infectious disease consultations with a rapid microbiological identification system (Verigene system) for Gram-positive and Gram-negative bacteremia
Japan |
Gram-positive and Gram-negative bacteremia
Infectious disease |
Others
NO
The purpose of this study is to evaluate the clinical significance of rapid identification with the Verigene system for Gram-positive and Gram-negative bacteremia by comparing it with conventional microbiological identification methods.
Others
Efficacy
Confirmatory
Pragmatic
Not applicable
Duration before the initiation of appropriate antimicrobial therapy after obtaining blood cultures.
1)Additional cost requirement of antimicrobial agents compared with appropriate antimicrobial therapy
2)14 days mortality
3)30 days mortality
Interventional
Parallel
Non-randomized
Open -no one is blinded
Active
2
Treatment
Device,equipment |
1)Control
Clinical management with conventional microbiological identification methods.
2)Intervention
Clinical management with conventional microbiological identification methods and Verigene system.
Not applicable |
Not applicable |
Male and Female
Gram-positive or Gram-negative bacteremia detected by BacT/Alert 3D system (Sysmex bioMerieux Co. Ltd., Tokyo, Japan).
1)If only one set of blood cultures is positive among two sets of blood cultures incubated, and Staphylococcus spp. or Gram-positive rods are suspected by Gram stain examination.
2)If one set of blood culture is positive with Staphylococcus spp. suspected by Gram stain examination and contamination is clinically considered.
3)If blood cultures are positive and Gram-positive rods are suspected in nosocomial bacteremia patients.
4)If differentiation between Gram-positive and Gram-negative bacteria is difficult by Gram stain examination.
5)If more than two species of bacteria are suspected by Gram stain examination.
6)If more than 24 hours have passed after positive blood culture alarm by BacT/Alert 3D system.
7)If Gram stain examination of positive blood culture indicates the same bacteria as previous positive blood culture obtained within the past week.
8)If patients have already been referred or transferred to other hospitals.
9)If patients are not hospitalized in Tsukuba Medical Center Hospital.
10)If palliative care is performed without treatment for infections.
11)If patients have already died at the time of reporting the results of Gram staining.
80
1st name | |
Middle name | |
Last name | Hiromichi Suzuki |
Tsukuba Medical Center Hospital
Division of Infectious Diseases, Department of Medicine/Department of Clinical Laboratory Medicine
1-3-1 Amakubo, Tsukuba, Ibaraki
029-851-3511
hsuzuki@tmch.or.jp
1st name | |
Middle name | |
Last name | Hiromichi Suzuki |
Tsukuba Medical Center Hospital
Division of Infectious Diseases, Department of Medicine/Department of Clinical Laboratory Medicine
1-3-1 Amakubo, Tsukuba, Ibaraki
029-851-3511
http://www.tmch.or.jp/hosp/
hsuzuki@tmch.or.jp
Tsukuba Medical Center Hospital
Hitachi High-Technologies Corporation
Profit organization
Japan
Miroku Medical Laboratory Inc.
Tsukuba Medical Center Hospital
NO
筑波メディカルセンター病院(茨城県)、ミロクメディカルラボラトリー(長野県)
2014 | Year | 06 | Month | 29 | Day |
Published
Completed
2014 | Year | 06 | Month | 04 | Day |
2014 | Year | 07 | Month | 01 | Day |
2015 | Year | 01 | Month | 30 | Day |
2014 | Year | 06 | Month | 27 | Day |
2016 | Year | 06 | Month | 27 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000016547
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