Unique ID issued by UMIN | UMIN000014565 |
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Receipt number | R000016900 |
Scientific Title | Postoperative pain was successfully treated with 8 mcg/kg of transitional fentanyl following high dose remifentanil anesthesia. |
Date of disclosure of the study information | 2014/09/01 |
Last modified on | 2014/07/15 17:07:01 |
Postoperative pain was successfully treated with 8 mcg/kg of transitional fentanyl following high dose remifentanil anesthesia.
Postoperative pain was successfully treated with 8 mcg/kg of transitional fentanyl following high dose remifentanil anesthesia.
Postoperative pain was successfully treated with 8 mcg/kg of transitional fentanyl following high dose remifentanil anesthesia.
Postoperative pain was successfully treated with 8 mcg/kg of transitional fentanyl following high dose remifentanil anesthesia.
Japan |
jaw deformity
Anesthesiology |
Others
NO
The present study was performed to investigate whether the administration of 8 mcg/kg transitional fentanyl could reduce postoperative fentanyl consumption following high-dose remifentanil anesthesia.
Pharmacodynamics
Amount of fentanyl administered within 24 hours after surgery.
Visual analog scale (VAS) values at 1, 3, 6, and 24 hours after surgery.
Estimated effect-site concentrations of both fentanyl and remifentanil at extubation.
Time from the completion of surgery to the extubation.
Side-effects.
Interventional
Parallel
Randomized
Open -but assessor(s) are blinded
Dose comparison
2
Treatment
Medicine |
Administration of 1 mcg/kg/min of remifentanil combined with 4 mcg/kg transitional fentanyl.
Administration of 1 mcg/kg/min of remifentanil combined with 8 mcg/kg transitional fentanyl.
16 | years-old | <= |
50 | years-old | >= |
Male and Female
patients who undergoing orthognathic surgery were included in this study.
American Society of Anesthesiologists (ASA) physical status I-II.
they had obesity (body mass index over 30 kg/m2);
could not be extubated immediately after surgery;
had been treated any analgesic drug within 24 hours prior to surgery;
had a history of chronic pain, drug or alcohol abuse, or psychiatric disease;
and had contraindications to the self-administration of opioids [i.e. they were unable to understand the patient-controlled analgesia (PCA) device].
30
1st name | |
Middle name | |
Last name | Kyotaro Koshika |
Tokyo Dental College Ichikawa General Hospital
Department of Anesthesiology
5-11-13 Sugano, Ichikawa-shi, Chiba-ken, Japan
047-322-0151
koshikakyotarou@tdc.ac.jp
1st name | |
Middle name | |
Last name | Kyotaro Koshika |
Tokyo Dental College Ichikawa General Hospital
Department of Anesthesiology
5-11-13 Sugano, Ichikawa-shi, Chiba-ken, Japan
047-322-0151
koshikakyotarou@tdc.ac.jp
Department of Anesthesiology, Tokyo Dental College Ichikawa General Hospital
MSD K.K.
Profit organization
AstraZeneca K.K.
NO
東京歯科大学市川総合病院(千葉県)
2014 | Year | 09 | Month | 01 | Day |
Partially published
No longer recruiting
2011 | Year | 04 | Month | 01 | Day |
2011 | Year | 09 | Month | 02 | Day |
2014 | Year | 07 | Month | 15 | Day |
2014 | Year | 07 | Month | 15 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000016900
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