Unique ID issued by UMIN | UMIN000039532 |
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Receipt number | R000017470 |
Scientific Title | Objective evaluation by functional near-infrared spectroscopy(fNIRS) of the relationship between color tone and photophobia in patients with the eye diseases. |
Date of disclosure of the study information | 2020/03/01 |
Last modified on | 2021/08/24 19:32:49 |
Objective evaluation by functional near-infrared spectroscopy(fNIRS) of the relationship between color tone and photophobia in patients with the eye diseases.
Objective evaluation of photophobia.
Objective evaluation by functional near-infrared spectroscopy(fNIRS) of the relationship between color tone and photophobia in patients with the eye diseases.
Objective evaluation of photophobia.
Japan |
Retinal degeneration group (including retinitis pigmentosa), eyelid and facial muscle spasm group (including hemifacial spasm and blepharospasm), ocular surface disorder group (including dry eye), and nerve atrophy group (including advanced glaucoma).
Ophthalmology |
Others
NO
Objective quantitative evaluation of photophobia, a symptom that occurs in various pathologies, is difficult. Previously we objectively evaluated photophobia in normal subjects under mydriasis with light load by assessing frontal lobe activation by fNIRS (functional near infrared spectroscopy) and physiological changes in blink frequency while adjusting light load by changing color filters. In this study, we evaluated whether photophobia in patients with the eye diseases could be assessed by this method.
Efficacy
Confirmatory
Not applicable
Objective quantitative evaluation of photophobia.
Determination of photophobia reduce color by each disease.
Interventional
Single arm
Non-randomized
Open -no one is blinded
Self control
1
Diagnosis
Device,equipment |
Frontal lobe activation measurement using fNIRS (functional near-infrared spectroscopy) under four conditions with 1000 lx light load for 1.5 minutes.
20 | years-old | <= |
90 | years-old | >= |
Male and Female
Retinal degeneration group (including retinitis pigmentosa), eyelid and facial muscle spasm group (including hemifacial spasm and blepharospasm), ocular surface disorder group (including dry eye), and nerve atrophy group (including advanced glaucoma) with photophobia.
Unstable medical condition
Unmeasurable
Eyelid opening impossible in light load of 1000 lx
Expected of phototoxic
Obvious misalignment of the eyes
If you think researchers unsuitable
24
1st name | Masafumi |
Middle name | |
Last name | Ono |
Nippon Medical School
Department of Ophthalmology
1138603
1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8603 JAPAN
0338222131
ono@nms.ac.jp
1st name | Masafumi |
Middle name | |
Last name | Ono |
Nippon Medical School
Department of Ophthalmology
1138603
1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8603 JAPAN
03-3822-2131
ono@nms.ac.jp
Nippon Medical School
Tokai Optical Co., Ltd.
Profit organization
Nippon Medical School
1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8603 JAPAN
03-3822-2131
inq-ccr@nms.ac.jp
NO
2020 | Year | 03 | Month | 01 | Day |
Unpublished
33
Completed
2012 | Year | 11 | Month | 01 | Day |
2013 | Year | 04 | Month | 10 | Day |
2013 | Year | 04 | Month | 10 | Day |
2020 | Year | 08 | Month | 31 | Day |
2020 | Year | 02 | Month | 19 | Day |
2021 | Year | 08 | Month | 24 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000017470
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