Unique ID issued by UMIN | UMIN000015579 |
---|---|
Receipt number | R000018105 |
Scientific Title | Research for selecting opioid using biomarker for cancer pain |
Date of disclosure of the study information | 2014/11/04 |
Last modified on | 2021/11/10 18:17:04 |
Research for selecting opioid using biomarker for cancer pain
RELIEF STUDY
Research for selecting opioid using biomarker for cancer pain
RELIEF STUDY
Japan |
Cancer Pain
Hematology and clinical oncology | Psychosomatic Internal Medicine |
Malignancy
YES
The comparison of required dose of opioid
between genomic differences
Safety,Efficacy
Confirmatory
Phase III
The rate of high dose opioid on Day0
Interventional
Parallel
Randomized
Individual
Open -no one is blinded
Active
YES
4
Treatment
Medicine | Gene |
morphine COMT GG
oxycodone COMT GG
morphine COMT Non-GG
oxycodone COMT Non-GG
Not applicable |
Not applicable |
Male and Female
First screening registration entry
1 Patients with advanced malignant tumors
2 Opioid non daily use patients
Secondary screening registration entry
1 Cancer pain,that is targeted for the opioid treatment,taking NSAIDs or acetaminophen
2 NRS is 3 or more
3 Opioid treatment naive within 30 hours
4 Patients who have no influence on previous chemotherapy, radiation therapy
5 Written informed consent
1) patients with chronic renal failure (glomerular filtration rate, 30 mL/min),
2) patients with severe hepatic or respiratory failure
3) patients deemed ineligible for the study by the study coordinator or a collaborative investigator
140
1st name | |
Middle name | |
Last name | Kazuhiko Nakagawa |
Kinki University, Faculty of Medicine
Department of Medical Oncology
377-2, Ohno-higashi, Osakasayama City, Osaka, 589-8511
072-366-0221
nakagawa@med.kindai.ac.jp
1st name | |
Middle name | |
Last name | Hiromichi Matsuoka |
Kinki University, Faculty of Medicine
Palliative Care Center
377-2, Ohno-higashi, Osakasayama City, Osaka, 589-8511
072-366-0221
matsuoka_h@med.kindai.ac.jp
Department of Medical Oncology
Japan Agency for Medical Research and Development
Japanese Governmental office
NO
2014 | Year | 11 | Month | 04 | Day |
Unpublished
Completed
2014 | Year | 09 | Month | 22 | Day |
2014 | Year | 09 | Month | 22 | Day |
2014 | Year | 11 | Month | 04 | Day |
2020 | Year | 02 | Month | 21 | Day |
2014 | Year | 11 | Month | 01 | Day |
2021 | Year | 11 | Month | 10 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000018105
Research Plan | |
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Research case data specifications | |
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Research case data | |
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