Unique ID issued by UMIN | UMIN000015611 |
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Receipt number | R000018142 |
Scientific Title | The clinical trials for pain relief and side effects of anti VEGF therapy for chronic lumbar discogenic low back pain -Part I ,II phase test - |
Date of disclosure of the study information | 2015/05/01 |
Last modified on | 2015/05/01 18:17:59 |
The clinical trials for pain relief and side effects of anti VEGF therapy for chronic lumbar discogenic low back pain -Part I ,II phase test -
Anti-VEGF therapy for discogenic low back pain
The clinical trials for pain relief and side effects of anti VEGF therapy for chronic lumbar discogenic low back pain -Part I ,II phase test -
Anti-VEGF therapy for discogenic low back pain
Japan |
Discogenic low back pain
Orthopedics |
Others
NO
the purpose of this study is evaluation and investigation of the therapeutic and adverse effects of anti-VEGF therapy for low back pain
Safety,Efficacy
Exploratory
Others
Phase I,II
low back pain visual analog scale(VAS)
Parallel
Randomized
Individual
Single blind -participants are blinded
Active
2
Treatment
Medicine |
intradiscal administration of local anesthetic agent(bupivacaine)and pegaputanib Na group
intradiscal administration of local anesthetic agent (bupivacaine)group
15 | years-old | <= |
80 | years-old | > |
Male and Female
1.low back pain,leg pain
2.X-ray and MRI can explain the condition
3.less than 2 disc degeneration
4.Spinal instability
5.agreement with this study
6.refractory to 3 months of conservative treatments
1.loss of consiousness
2.case with history of spinal surgery, infection
3.severe systemic complications
4.diabetes mellitus
5.psychiatric disease
6.pregnant women and women suspected of being pregnant
7.case with malignancy
8.the case considered to be unsuitable as a subject
30
1st name | |
Middle name | |
Last name | Ohtori Seiji |
Graduate School of Medicine, Chiba University
Department of Orthopaedic Surgery
1-8-1 Inohana, Chuo-ku, Chiba
043-226-2117
sohotri@faculty.chiba-u.jp
1st name | |
Middle name | |
Last name | Sato Jun |
Graduate School of Medicine, Chiba University
Department of Orthopaedic Surgery
1-8-1 Inohana, Chuo-ku, Chiba
043-226-2117
scottie6242000@yahoo.co.jp
Department of Orthopaedic Surgery,Graduate School of Medicine,Chiba University
AO spine
Non profit foundation
NO
2015 | Year | 05 | Month | 01 | Day |
Published
Completed
2013 | Year | 10 | Month | 01 | Day |
2014 | Year | 01 | Month | 08 | Day |
2014 | Year | 11 | Month | 05 | Day |
2015 | Year | 05 | Month | 01 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000018142
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