Unique ID issued by UMIN | UMIN000015854 |
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Receipt number | R000018450 |
Scientific Title | Comparison of the efficacy of branched chain amino acid with maltodextrin in outpatient rehabilitation for elderly adults with disabilities: Cross-over trial |
Date of disclosure of the study information | 2014/12/04 |
Last modified on | 2020/07/13 09:33:05 |
Comparison of the efficacy of branched chain amino acid with maltodextrin in outpatient rehabilitation for elderly adults with disabilities: Cross-over trial
Comparison of the efficacy of amino acid with dextrin in outpatient rehabilitation for elderly adults
Comparison of the efficacy of branched chain amino acid with maltodextrin in outpatient rehabilitation for elderly adults with disabilities: Cross-over trial
Comparison of the efficacy of amino acid with dextrin in outpatient rehabilitation for elderly adults
Japan |
Elderly adults with disabilities
Rehabilitation medicine |
Others
NO
Using cross-over trial, This study examined the efficacy of one or two session a week of exercise combined with branched chain amino acid supplementation to physical function.
Efficacy
Exploratory
Pragmatic
Not applicable
Upper and lower limb isometric strength(Leg press, abduction, knee extension, Rowing)
Physical activity
(Frenchay activities index)
Grip strength
Performance test
(Timed up and go test, Functional reach test)
Interventional
Cross-over
Randomized
Individual
Single blind -participants are blinded
Dose comparison
NO
NO
Institution is not considered as adjustment factor.
NO
Pseudo-randomization
2
Treatment
Food |
Branched amino acid supplement
6g/ 3 months
Washout period/ 1 month
Maltodextrin 6g/ 3 months
Maltodextrin 6g/ 3 months
Washout period/ 1 month
Branched amino acid supplement
6g/ 3 months
40 | years-old | <= |
Not applicable |
Male and Female
1) Elderly adults with disabilities, Japanese who utilize Long-term Care Insurance.
2) Eligible to training with utilize of muscle training machine.
1)Persons with deglutition disorder
2)Persons with dementia
3)Persons with diabetes who need to insulin injections
4)Persons with progressive disorder of the nervous system and muscle
5)Persons with the depression or schizophrenic disorder
6)Persons with untreated cardiovascular disorder
7)Persons with renal disorder who need to dietary restriction
8)Persons who need to limitetion of physical activity
51
1st name | Takashi |
Middle name | |
Last name | Ikeda |
Tokyo Medical and Dental University Graduate school
Department of Rehabilitation Medicine
113-8510
1-5-45, Yushima, Bunkyo-ku, Tokyo 113-8510, Japan
+81-03-3813-6111
tikeda-tmd@umin.ac.jp
1st name | Takashi |
Middle name | |
Last name | Ikeda |
Tokyo Medical and Dental University Graduate school
Department of Rehabilitation Medicine
113-8510
1-5-45, Yushima, Bunkyo-ku, Tokyo 113-8510, Japan
+81-03-3813-6111
tikeda-tmd@umin.ac.jp
Shonan Kamakura general hospital
Japanese Physical Therapy Association
Other
Japan
none
none
Tokushukai Group Ethical Committee
1-8-7,Koji-machi,Chiyoda-ku,Tokyo 102-0083,Japan
+81-03-3263-4801
hisamatsu@mirai-iryo.com
NO
介護老人保健施設リハビリケア湘南かまくら(神奈川)/Rehabil-Care Shonan Kamakura (health services facility for the aged)(Kanagawa, Japan)
2014 | Year | 12 | Month | 04 | Day |
none
Published
https://doi.org/10.1139/apnm-2015-0436
52
Using a crossover design, we investigated the effects of exercise therapy combined with BCAA intake on physical function improvement in frail and pre-frail elderly people requiring longterm care. Significant improvements in gross lower limb muscle strength and dynamic balance ability were achieved by combining BCAA intake and exercise therapy. Therefore, it is feasible to achieve these effects using this combined therapy.
2020 | Year | 07 | Month | 13 | Day |
Eligible persons were 80 frail and pre-frail elderly adults requiring
long-term care who received outpatient rehabilitation at a
health services facility for the aged.
A single-blinded, randomized, crossover experimental design,with two 3-month periods of exercise with supplementation and a
1-month washout period of exercise without supplementation,
was used.
none
Evaluations were conducted before starting the intervention, after each 3-month supplementation period (cycles A and B), and after the washout period. Investigators were not blind to group allocation. Investigators determined upper and lower limb isometric strength, grip strength, Timed Up and Go test (TUG) and Functional Reach Test (FRT) performance, Frenchay Activities Index(FAI), and the number of rehabilitation sessions. The following demographic data were collected from clinical records: age, sex, body mass index (BMI), comorbidity index, duration of outpatient rehabilitation, and underlying diseases (cranial nerve disease, musculoskeletal disease, and peripheral cardiovascular disease).
Completed
2013 | Year | 08 | Month | 12 | Day |
2013 | Year | 08 | Month | 12 | Day |
2013 | Year | 08 | Month | 20 | Day |
2014 | Year | 04 | Month | 30 | Day |
2014 | Year | 05 | Month | 30 | Day |
2014 | Year | 05 | Month | 30 | Day |
2014 | Year | 10 | Month | 31 | Day |
none
2014 | Year | 12 | Month | 04 | Day |
2020 | Year | 07 | Month | 13 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000018450
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