Unique ID issued by UMIN | UMIN000015912 |
---|---|
Receipt number | R000018481 |
Scientific Title | Efficacy of maintenance therapy with adalimumab in ulcerative colitis achieving remission with tacrolimus |
Date of disclosure of the study information | 2014/12/15 |
Last modified on | 2018/12/20 22:28:47 |
Efficacy of maintenance therapy with adalimumab in ulcerative colitis achieving remission with tacrolimus
Efficacy of maintenance therapy with adalimumab in ulcerative colitis achieving remission with tacrolimus
Efficacy of maintenance therapy with adalimumab in ulcerative colitis achieving remission with tacrolimus
Efficacy of maintenance therapy with adalimumab in ulcerative colitis achieving remission with tacrolimus
Japan |
ulcerative colitis
Gastroenterology |
Others
NO
The aim of this study is to evaluate the efficacy of maintenance therapy with adalimumab in ulcerative colitis achieving remission with tacrolimus
Efficacy
Not applicable
Clinical remission rate
Endoscopic remission rate
Interventional
Parallel
Randomized
Individual
Open -no one is blinded
Active
NO
NO
Institution is not considered as adjustment factor.
NO
Numbered container method
2
Treatment
Medicine |
Tacrolimus will be decreased gradually three months after it was administered.
Adalimumab will be administrated three months after tacrolimus was administered, and tacrolimus will be decreased gradually.
16 | years-old | <= |
70 | years-old | > |
Male and Female
Patients with ulcerative colitis treated with tacrolimus and achieved clinical remission at month 3.
Patients who does not achieved mucosal healing by colonoscopy.
Mucosal healing is defined as a Mayo endoscopic score of 0.
Antibiotics naive patients
Patients who are applied to the medically contraindicated of adalimumab
Patients who are determined to be inappropriate for administration of adalimumab by doctors
50
1st name | |
Middle name | |
Last name | Takuya Inoue |
Osaka Medical College Hospital
2nd Department of Internal Medicine
2-7, Daigaku-cho, Takatsuki-shi, Osaka, Japan
072-683-1221
ureuretakuwan@yahoo.co.jp
1st name | |
Middle name | |
Last name | Kazuki Kakimoto |
Osaka Medical College Hospital
2nd Department of Internal Medicine
2-7, Daigaku-cho, Takatsuki-shi, Osaka, Japan
072-683-1221
in2098@poh.osaka-med.ac.jp
Osaka Medical College
None
Self funding
NO
2014 | Year | 12 | Month | 15 | Day |
Unpublished
Open public recruiting
2014 | Year | 10 | Month | 01 | Day |
2014 | Year | 12 | Month | 15 | Day |
2014 | Year | 12 | Month | 10 | Day |
2018 | Year | 12 | Month | 20 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000018481
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