Unique ID issued by UMIN | UMIN000015889 |
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Receipt number | R000018495 |
Scientific Title | Effects of tramadol on cognitive functions in normal subjects using fMRI |
Date of disclosure of the study information | 2014/12/10 |
Last modified on | 2016/10/04 17:03:36 |
Effects of tramadol on cognitive functions in normal subjects using fMRI
Effects of tramadol on cognitive functions in normal subjects using fMRI
Effects of tramadol on cognitive functions in normal subjects using fMRI
Effects of tramadol on cognitive functions in normal subjects using fMRI
Japan |
Healthy adults
Adult |
Others
NO
The aim of this study is to investigate the effects of tramadol on human cognitive functions.
Efficacy
Comparison of BOLD signal changes measured by fMRI between placebo and tramadol conditions
Interventional
Cross-over
Randomized
Individual
Double blind -all involved are blinded
Placebo
2
Prevention
Medicine |
1 day, 1 time, tramadol 50mg
washout duration 1 week
1 day, 1 time, placebo
1 day, 1 time, placebo
washout duration 1 week
1 day, 1 time, tramadol 50mg
20 | years-old | <= |
40 | years-old | > |
Male and Female
Subjects with no history of psychiatric disorders.
Subjects who have the ability to provide informed consent and adhere to the protocol.
Subjects with drug allergy.
Subjects with history of epilepsy or seizure.
Subjects taking drugs within 2 weeks of the trial.
Subjects with liver or renal dysfunction.
Subjects who have tendency to drug abuse or drug dependence.
Pregnant woman and woman suspected of being pregnant.
Woman who is breastfeeding.
Subjects with contraindications to MRI.
Subjects who are judged as not suitable for participation in this study.
35
1st name | |
Middle name | |
Last name | Hidenori Suzuki |
Nippon Medical School
Department of Pharmacology
1-1-5, Sendagi, Bunkyo-ku, Tokyo
03-3822-2131
hsuzuki@nms.ac.jp
1st name | |
Middle name | |
Last name | Yumiko Ikeda |
Nippon Medical School
Department of Pharmacology
1-1-5, Sendagi, Bunkyo-ku, Tokyo
03-3822-2131
y-ikeda@nms.ac.jp
Nippon Medical School
Ministry of Education, Culture, Sports, Science and Technology
Japanese Governmental office
NO
2014 | Year | 12 | Month | 10 | Day |
Unpublished
Open public recruiting
2014 | Year | 11 | Month | 04 | Day |
2014 | Year | 12 | Month | 10 | Day |
2014 | Year | 12 | Month | 10 | Day |
2016 | Year | 10 | Month | 04 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000018495
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