Unique ID issued by UMIN | UMIN000015978 |
---|---|
Receipt number | R000018583 |
Scientific Title | Establishment of assay system for zinc in whole blood |
Date of disclosure of the study information | 2014/12/17 |
Last modified on | 2018/12/19 16:17:14 |
Establishment of assay system for zinc in whole blood
Assay system for zinc
Establishment of assay system for zinc in whole blood
Assay system for zinc
Japan |
Zinc deficiency
Medicine in general | Adult |
Others
NO
Plasma zinc level is assayable,but total zinc stored in whole body is not measurable,yet. In order to estimate stored zinc in whole body, we would like to establish to assay zinc in red blood cells.
Others
Zinc level in plasma and red blood cells will be measured befor and after uptake of zinc supplement.
Others
Others
Not applicable
Zinc content in red blood cells can be measured using the assay system for plasama zinc.
After uptake of zinc supplement, zinc contents in both plasma and red cells demonstrate increment.
Interventional
Cross-over
Non-randomized
Open -no one is blinded
No treatment
NO
NO
Institution is not considered as adjustment factor.
NO
No need to know
2
Diagnosis
Medicine |
To intake zinc-containing supplement.Seven days, at the regular supplement doses.
To draw peripheral blood before and after the inake of zinc supplement.
About 15 ml for blood cell count,chemistry and zinc level measurement.
20 | years-old | <= |
65 | years-old | > |
Male and Female
Nothing
Nothing
20
1st name | |
Middle name | |
Last name | Kenji Ikebuchi |
Saitama Medical University International Medical Center
Laboratory Department
1397-1, Yamane, Hidaka City, Saitama, Japan
042-984-4383
ikebuchi@saitama-med.ac.jp
1st name | |
Middle name | |
Last name | Kenji Ikebuchi |
Saitama Medical University International Medical Center
Laboratory Medicine Department
1397-1,Yamane, Hidaka City, Saitama
042-984-4383
ikebuchi@saitama-med.ac.jp
Saitama Medical University International Medical Center
Saitama Medical University
Other
Japan
Nothing
Nothing
NO
2014 | Year | 12 | Month | 17 | Day |
Unpublished
After lyzing total blood and red blood cells, supernatant solution samples were analysed its zinc content. The red color of the samples disturbed the colorimetoric assay and 20x dilution was necessary to assay. The intake of zinc supplement did not induced the increase of zinc storage volume in red blood cells and total blood. Seven days intake was not sufficient.
Completed
2014 | Year | 09 | Month | 03 | Day |
2014 | Year | 12 | Month | 17 | Day |
2015 | Year | 08 | Month | 31 | Day |
2015 | Year | 08 | Month | 31 | Day |
2015 | Year | 08 | Month | 31 | Day |
2016 | Year | 01 | Month | 30 | Day |
2014 | Year | 12 | Month | 17 | Day |
2018 | Year | 12 | Month | 19 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000018583
Research Plan | |
---|---|
Registered date | File name |
Research case data specifications | |
---|---|
Registered date | File name |
Research case data | |
---|---|
Registered date | File name |