Unique ID issued by UMIN | UMIN000016343 |
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Receipt number | R000018970 |
Scientific Title | The Nationwide Cancer Genome Screening Project for Gastrointestinal Cancer in Japan (SCRUM-Japan GI-SCREEN):Efficient Identification of Actionable Cancer Genome Alterations in Advanced Colorectal Cancer (GI-SCREEN 2013-01) |
Date of disclosure of the study information | 2015/01/26 |
Last modified on | 2022/05/10 19:48:07 |
The Nationwide Cancer Genome Screening Project for Gastrointestinal Cancer in Japan (SCRUM-Japan GI-SCREEN):Efficient Identification of Actionable Cancer Genome Alterations in Advanced Colorectal Cancer (GI-SCREEN 2013-01)
SCRUM-Japan GI-screen 2013-01-CRC
The Nationwide Cancer Genome Screening Project for Gastrointestinal Cancer in Japan (SCRUM-Japan GI-SCREEN):Efficient Identification of Actionable Cancer Genome Alterations in Advanced Colorectal Cancer (GI-SCREEN 2013-01)
SCRUM-Japan GI-screen 2013-01-CRC
Japan |
Colorectal cancer
Gastroenterology |
Malignancy
YES
To evaluate the frequency of characteristics of cancer genome alterations in advanced CRCs
Others
To evaluate the characteristics of cancer genome alterations in advanced CRCs,Quality of the specimen contributing to gene analysis
Frequency or characteristics of cancer genome alterations such as KRAS minor, BRAF, NRAS, PIK3CA in CRC
Association between each cancer genome alterations and clinicopathological characteristics or prognosis,Quality of the specimen contributing to gene analysis
Observational
Not applicable |
Not applicable |
Male and Female
1) Patients with histologically confirmed or clinically suspected advanced CRC (aCRC)
2) Planned to receive systemic chemotherapy for aCRC
3) KRAS exon 2 (codon12, 13) mutations were or will be determined
4) Presence or ability to acquire sufficient DNA for target sequencing
5) Written informed consent was obtained
1) Patient is judged by the investigator to be inappropriate for study participation for any reason.
1500
1st name | Takayuki |
Middle name | |
Last name | Yoshino |
National Cancer Center Hospital East
Gastrointestinal Oncology Division
277-8577
6-5-1, Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan
81-47-133-1111
tyoshino@east.ncc.go.jp
1st name | Kohei |
Middle name | |
Last name | Shitara |
National Cancer Center Hospital East
Gastrointestinal Oncology Division
277-8577
6-5-1, Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan
81-47-133-1111
kshitara@east.ncc.go.jp
National Cancer Center Hospital East
SCRUM Japan
Other
National Cancer Center Institutional Review Board
5-1-1, tsukiji, chuo-ku, tokyo
03-3542-2511
NCC_IRBoffice@ml.res.ncc.go.jp
NO
2015 | Year | 01 | Month | 26 | Day |
Unpublished
3641
Completed
2013 | Year | 12 | Month | 25 | Day |
2013 | Year | 12 | Month | 25 | Day |
2014 | Year | 02 | Month | 05 | Day |
2022 | Year | 03 | Month | 31 | Day |
2022 | Year | 03 | Month | 31 | Day |
characteristics of cancer genome alterations such as KRAS minor, BRAF, NRAS, PIK3CA and etc in advanced CRCs,Quality of the specimen contributing to gene analysis
2015 | Year | 01 | Month | 26 | Day |
2022 | Year | 05 | Month | 10 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000018970
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