Unique ID issued by UMIN | UMIN000016511 |
---|---|
Receipt number | R000019175 |
Scientific Title | SpO2 area of the 6 minute-walk test |
Date of disclosure of the study information | 2015/02/16 |
Last modified on | 2021/02/22 12:26:15 |
SpO2 area of the 6 minute-walk test
SpO2 area of the 6 minute-walk test
SpO2 area of the 6 minute-walk test
SpO2 area of the 6 minute-walk test
Japan |
Idiopathic pulmonary fibrosis
Chronic Obstructive Pulmonary Disesase
Combined Pulmonary Fibrosis and Emphysema
Pneumology |
Others
NO
To investigate the usefulness of the SpO2 area in patients with IPF/COPD/CPFE.
Efficacy
Change in SpO2 area
1.Change in 6 minute-walk distance.
2.Changes in pulmonary function test(VC, FVC, FEV1, FEV1/FVC, DLco, DLco/VA, R5, R20, R5-R20, X5, Fres, ALX).
Observational
40 | years-old | <= |
Not applicable |
Male and Female
1. FVC>1.0L in IPF/CPFE patients
2. 30%<=%FEV1<80% in COPD patients
3. all patients provide written informed consent.
1. patients who received therapy of the lung cancer.
2. patient who have treatment with the home oxygen therapy.
3. patients who had a history of the angina pectoralis within 1 month.
4. patient who have walking disturbance.
5. considered ineligible for the study by the investigator.
60
1st name | Akito |
Middle name | |
Last name | Yamamoto |
Shizuoka General Hospital
Respiratory medicine
420-8527
4-27-,Kita-ando,Aoi-ward,Shizuoka,Shizuoka,Japan
054-247-6111
akito-yamamoto@i.shizuoka-pho.jp
1st name | Akito |
Middle name | |
Last name | Yamamoto |
Shizuoka General Hospital
Respiratory medicine
420-8527
4-27-,Kita-ando,Aoi-ward,Shizuoka,Shizuoka,Japan
054-247-6111
akito-yamamoto@i.shizuoka-pho.jp
Shizuoka General Hospital
Shizuoka General Hospital
Self funding
Shizuoka General Hospital
4-27-,Kita-ando,Aoi-ward,Shizuoka,Shizuoka,Japan
054-247-6111
chiken-sougou@shizuoka-pho.jp
NO
2015 | Year | 02 | Month | 16 | Day |
https://www.tandfonline.com/doi/full/10.1080/15412555.2020.1844176
Published
https://www.tandfonline.com/doi/full/10.1080/15412555.2020.1844176
57
In multivariate regression analysis, a 6MWD less than 350m was independently predicted by CAT scores and inspiratory R5. In ROC, the AUC was 0.76, 0.78, and 0.85 for CAT scores, R5, and CAT scores plus R5, respectively, with the best cutoff value of 17 and 2.82 cmH20/L/s. In conclusion, inspiratory R5, predicted low exercise tolerance in COPD subjects.
2021 | Year | 02 | Month | 22 | Day |
This was a prospective, observational study. Fifty-seven subjects with COPD who attended outpatient clinics for routine checkups at Shizuoka General Hospital between April 2015 and April 2016.
Of the 57 total subjects, 43 (75.4%) had a 6MWD and over 350m, and 14 (24.6%) had a 6MWD less than 350m.
None, as this is an observational study.
Modified MRC dyspnea scale (mMRC), COPD Assessment Test (CAT), oscillometry, spirometry, and 6MWT were performed in a stable condition. The participants were classified into subjects with 6MWD and over 350m or 6MWD less than 350m, and the predictor of 6MWD less than 350m was assessed.
Main results already published
2015 | Year | 01 | Month | 27 | Day |
2015 | Year | 01 | Month | 27 | Day |
2015 | Year | 02 | Month | 16 | Day |
2017 | Year | 11 | Month | 30 | Day |
2017 | Year | 11 | Month | 30 | Day |
2018 | Year | 02 | Month | 01 | Day |
Study design
1. A prospective, obserbational study
2. Method: To compare changes in Pulmnary Function Test,6 minute-walk test. 1-year changes for patients with mild to moderate stable IPF/COPD/CPFE.
2015 | Year | 02 | Month | 11 | Day |
2021 | Year | 02 | Month | 22 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000019175
Research Plan | |
---|---|
Registered date | File name |
Research case data specifications | |
---|---|
Registered date | File name |
Research case data | |
---|---|
Registered date | File name |