Unique ID issued by UMIN | UMIN000016675 |
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Receipt number | R000019261 |
Scientific Title | Morphological and Functional Change of Coronary Perivascular Adipose Tissue in Vasospastic Angina |
Date of disclosure of the study information | 2015/03/09 |
Last modified on | 2018/03/04 12:00:19 |
Morphological and Functional Change of Coronary Perivascular Adipose Tissue in Vasospastic Angina
ADIPO-VSA Trial
Morphological and Functional Change of Coronary Perivascular Adipose Tissue in Vasospastic Angina
ADIPO-VSA Trial
Japan |
Vasospastic angina
Medicine in general | Cardiology | Radiology |
Others
NO
The purpose of this study is to investigate the relationship between vasospastic angina and morphological and functional change of coronary perivascular adipose tissue.
Others
Morphological change of coronary perivascular adipose tissue is assessed by volume measured by cardiac CT, functional change is assessed by FDG-uptake measured by 18F-FDG PET.
Exploratory
Pragmatic
(1)Coronary perivascular adipose tissue volume measured by cardiac CT.
(2)FDG-uptake of coronary perivascular adipose tissue measured by 18F-FDG PET.
(3)FDG-uptake of vascular wall in which vasospasm occurs measured by 18F-FDG PET.
(4)Vasa vasorum measured by OFDI
(5)General blood examination deta, adiponectin, Rho-kinase activity
(6)Metabolite measured by metabolome analysis
(7)Exercise tolerance measured by cardiopulmonary exercise test
(8)FDG-uptake of coronary perivascular adipose tissue measured by 18F-FDG PET at the time of follow-up.
Observational
20 | years-old | <= |
Not applicable |
Male and Female
Patients who are suspected of vasospastic angina.
(1) Acute coronary syndrome
(2) EF is under 40%.
(3) Severe renal failure.
(4) Severe contrast media allergy
(5) history of cardiac surgery
(6) Severe asthma
(7) Diabetes which needs insulin therapy
150
1st name | |
Middle name | |
Last name | Hiroaki Shimokawa |
Tohoku University Hospital
Department of Cardiovascular Medicine
1-1 Seiryo-machi, Aoba-ku, Sendai, 980-8574 Japan
+81-22-717-7153
shimo@cardio.med.tohoku.ac.jp
1st name | |
Middle name | |
Last name | Yasuharu Matsumoto |
Tohoku University Hospital
Department of Cardiovascular Medicine
1-1 Seiryo-machi, Aoba-ku, Sendai, 980-8574 Japan
+81-22-717-7153
matsumoto@cardio.med.tohoku.ac.jp
Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
Mochida Memorial Foundation for Medical and Pharmaceutical Research
Non profit foundation
Banyu Life Science Foundation International
NO
東北大学病院(宮城県)
2015 | Year | 03 | Month | 09 | Day |
Published
Completed
2015 | Year | 03 | Month | 02 | Day |
2015 | Year | 03 | Month | 09 | Day |
2017 | Year | 07 | Month | 31 | Day |
2017 | Year | 07 | Month | 31 | Day |
2017 | Year | 07 | Month | 31 | Day |
2017 | Year | 12 | Month | 31 | Day |
Patient's information is blinded to a person analyzing data of CT and PET.
2015 | Year | 03 | Month | 02 | Day |
2018 | Year | 03 | Month | 04 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000019261
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