Unique ID issued by UMIN | UMIN000016622 |
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Receipt number | R000019299 |
Scientific Title | Effect of an antipsychotic drug on regulatory system of salience network through dopamine D2/3 receptors |
Date of disclosure of the study information | 2015/04/01 |
Last modified on | 2017/06/02 16:12:37 |
Effect of an antipsychotic drug on regulatory system of salience network through dopamine D2/3 receptors
Regulatory system of salience network through dopamine D2/3 receptors
Effect of an antipsychotic drug on regulatory system of salience network through dopamine D2/3 receptors
Regulatory system of salience network through dopamine D2/3 receptors
Japan |
schizophrenia
Psychiatry |
Others
NO
To investigate effects of antipsychotic risperidone on salience network in patients with schizophrenia
Pharmacokinetics
Exploratory
Relationship between functional connectivity in salience network and D2/3 receptor occupancy by risperidone in patients with schizophrenia.
Interventional
Parallel
Non-randomized
Open -no one is blinded
Placebo
2
Treatment
Device,equipment |
magnetic resonance imaging, blood sampling
magnetic resonance imaging
20 | years-old | <= |
50 | years-old | > |
Male and Female
<schizophrenia>
1. Patients with schizophrenia diagnosed by DSM-IV-TR taking risperiodone
2. over 20 years old, less than 50 years old
3. male and female
4. Those who can read and understand informed consent of the protocol
5. Those who are treated by risperidone
6. Those who do not take benzadiazepines
<healthy control>
1. Those who do not have psychiatric/severe physical disease
2. over 20 years old, less than 50 years old
3. male and female
<schizophrenia>
1. Those who have severe psychiatric symptom
2. Those who have other psychiatric disorder(s)
3. Those who have organic brain disease
4. Those who have severe physical disease
5. Those who pregnant or have a possibility of pregnancy
6. Those who have heart pace maker or other metal in their body
7. Those who have agrophobia
8. Those who have tatoo
9. Those who are considered as not eligible by principal investigator
<healthy control>
1.Those who pregnant or have a possibility of pregnancy
2. Those who have heart pace maker or other metal in their body
3. Those who have agrophobia
4. Those who have tatoo
5. Those who are considered as not eligible by principal investigator
60
1st name | |
Middle name | |
Last name | Kodaka Fumitoshi |
The Jikei University School of Medicine
Department of Psychiatry
3 Chome-25-8 Nishishinbashi, Minato, Tokyo
+81-3-3433-1111
kodaka@jikei.ac.jp
1st name | |
Middle name | |
Last name | Kodaka Fumitoshi |
The Jikei University School of Medicine
Department of Psychiatry
3 Chome-25-8 Nishishinbashi, Minato, Tokyo
+81-3-3433-1111
kodaka@jikei.ac.jp
The Jikei University School of Medicine
Japan Society for the Promotion of Science
Other
NO
2015 | Year | 04 | Month | 01 | Day |
Unpublished
Open public recruiting
2014 | Year | 02 | Month | 24 | Day |
2015 | Year | 04 | Month | 01 | Day |
2015 | Year | 02 | Month | 24 | Day |
2017 | Year | 06 | Month | 02 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000019299
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