Unique ID issued by UMIN | UMIN000016840 |
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Receipt number | R000019508 |
Scientific Title | Exploratory analyses of biomarker using change of blood free amino-acid concentration related to JPH203(LAT1 inhibitor). |
Date of disclosure of the study information | 2015/03/20 |
Last modified on | 2020/09/07 21:34:48 |
Exploratory analyses of biomarker using change of blood free amino-acid concentration related to JPH203(LAT1 inhibitor).
Exploratory analyses of biomarker using change of blood free amino-acid concentration related to JPH203(LAT1 inhibitor).
Exploratory analyses of biomarker using change of blood free amino-acid concentration related to JPH203(LAT1 inhibitor).
Exploratory analyses of biomarker using change of blood free amino-acid concentration related to JPH203(LAT1 inhibitor).
Japan |
Solid tumors
Gastroenterology | Hepato-biliary-pancreatic medicine | Gastrointestinal surgery |
Hepato-biliary-pancreatic surgery | Breast surgery | Urology |
Malignancy
NO
Exploratory research on change of blood free amino-acid concentration related to JPH203, and reveal biomarker related to efficacy of JPH203.
Bio-availability
Exploratory
Pragmatic
Not applicable
Identification of biomarker related to efficacy of JPH203.
To reveal difference in various tumors of blood free amino-acid concentration in patients with solid tumors.
Observational
20 | years-old | <= |
Not applicable |
Male and Female
Patients who are registered in JPH203-SBECD-PI study (UMIN000016546) and getting the informed consent from the patient.
Patients who refuse to supply the data.
21
1st name | |
Middle name | |
Last name | Junji Furuse |
School of Medicine, Kyorin University
Department of Internal Medicine, Medical Oncology
6-20-2, Shinkawa, Mitaka-shi, Tokyo, Japan
0422-47-5511
jfuruse@ks.kyorin-u.ac.jp
1st name | |
Middle name | |
Last name | Naohiro Okano |
School of Medicine, Kyorin University
Department of Internal Medicine, Medical Oncology
6-20-2, Shinkawa, Mitaka-shi, Tokyo, Japan
0422-47-5511
naohiro-okano@ks.kyorin-u.ac.jp
School of Medicine, Kyorin University
School of Medicine, Kyorin University
Self funding
NO
2015 | Year | 03 | Month | 20 | Day |
Published
http://iv.iiarjournals.org/content/34/5/2595.long
17
The LAT1 inhibitor JPH203 showed promising activity against biliary tract cancer and high body mass index patients because of having sufficient gradients of LAT1-substarte plasma free amino acids, especially branched chain amino acids.
2020 | Year | 09 | Month | 07 | Day |
Completed
2015 | Year | 02 | Month | 19 | Day |
2015 | Year | 03 | Month | 20 | Day |
Analysis for identification of biomarker related to efficacy data from phase I clinical trial in patients with solid tumors (JPH203-SBECD-PI study).
2015 | Year | 03 | Month | 19 | Day |
2020 | Year | 09 | Month | 07 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000019508
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