Unique ID issued by UMIN | UMIN000017351 |
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Receipt number | R000020137 |
Scientific Title | Effect of exposure of HCl, bile acid nitric oxide on epithelial mucosal injury in Barrett's esophagus - a study using biopsy specimen- |
Date of disclosure of the study information | 2016/01/01 |
Last modified on | 2015/04/30 18:22:57 |
Effect of exposure of HCl, bile acid nitric oxide on epithelial mucosal injury in Barrett's esophagus - a study using biopsy specimen-
Effect of exposure of HCl, bile acid nitric oxide on epithelial mucosal injury in Barrett's esophagus
Effect of exposure of HCl, bile acid nitric oxide on epithelial mucosal injury in Barrett's esophagus - a study using biopsy specimen-
Effect of exposure of HCl, bile acid nitric oxide on epithelial mucosal injury in Barrett's esophagus
Japan |
Barrett's esophagus
Gastroenterology |
Others
NO
To compare the responsiveness
of Barrett's epithelium and suquamous epithelium to ex vivo exposure to HCl, bile acid, and nitric oxide, using biopsy specimens from patients with Barrett's esophagus,
PK,PD
Comparison of epithelial resistance and permeability in ex vivo chamber system in response to exposure of HCl, bile acid, and nitric oxide
Interventional
Single arm
Non-randomized
Open -but assessor(s) are blinded
Uncontrolled
1
Prevention
Device,equipment |
taking endoscopic biopsy specimens
20 | years-old | <= |
Not applicable |
Male and Female
Patients with Barrett's esophagus
1. Taking antithrombotic drugs
2. Taking NSAIDs
3. bleeding tendancy
4. serious systematic diseases
50
1st name | |
Middle name | |
Last name | Iijima Katsunori |
Tohoku University Graduate Hospital
Division of Gastroenterology
1-1 Seiryo-machi, Aobaku, Sendai 980-8574, Japan
022-717-7171
kiijima@med.tohoku.ac.jp
1st name | |
Middle name | |
Last name | Iijima Katsunori |
Tohoku University Graduate Hospital
Division of Gastroenterology
1-1 Seiryo-machi, Aobaku, Sendai 980-8574, Japan
022-717-7171
kiijima@med.tohoku.ac.jp
Division of Gastroenterology, Tohoku University Graduate Hospital
Grant-in-Aid
NO
2016 | Year | 01 | Month | 01 | Day |
Unpublished
Preinitiation
2015 | Year | 01 | Month | 26 | Day |
2015 | Year | 08 | Month | 01 | Day |
2015 | Year | 04 | Month | 30 | Day |
2015 | Year | 04 | Month | 30 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000020137
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