Unique ID issued by UMIN | UMIN000017571 |
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Receipt number | R000020360 |
Scientific Title | The effect of anastrozole on bone mineral density during the first 5 years of adjuvant treatment in postmenopausal women with early breast cancer |
Date of disclosure of the study information | 2015/05/14 |
Last modified on | 2015/05/14 20:29:54 |
The effect of anastrozole on bone mineral density during the first 5 years of adjuvant treatment in postmenopausal women with early breast cancer
The effect of anastrozole on bone mineral density during the first 5 years of adjuvant treatment in postmenopausal women with early breast cancer
The effect of anastrozole on bone mineral density during the first 5 years of adjuvant treatment in postmenopausal women with early breast cancer
The effect of anastrozole on bone mineral density during the first 5 years of adjuvant treatment in postmenopausal women with early breast cancer
Japan |
Breast Cancer
Hematology and clinical oncology | Breast surgery |
Malignancy
NO
To clarify the effect of anastrozole on bone mineral density during the first 5 years of adjuvant treatment in postmenopausal women with early breast cancer
Safety
Confirmatory
Pragmatic
Not applicable
BMD change from baseline to 5 years at the lumbar spine and femoral neck
BMD change from baseline to 6, 12, 24, 36, 48 and 50 months at the lumbar spine and femoral neck
Bone fracture rate during 5 years
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
1
Treatment
Medicine |
Initiaion of bisphosphonate (risedronate or alendronate) when patients were diagnosed with osteoporosis having a T-score of -2.5 or lower.
50 | years-old | <= |
Not applicable |
Female
Primary breast cancer in stage 0 to IIIC
Treatment with anastrozole
Postmenopausal E2 <30pg/ml
Written informed concent
Patients already treated as osteoporosis
55
1st name | |
Middle name | |
Last name | Tadao Shimizu |
Tokyo Women's Medical University Medical Center East
Department of Breast Surgery
2-1-10 Nishiogu, Arakawa-ku, Tokyo 116-8567, Japan
03-3810-1111
shimitsu@dnh.twmu.ac.jp
1st name | |
Middle name | |
Last name | Akira Hirano |
Tokyo Women's Medical University Medical Center East
Department of Breast Surgery
2-1-10 Nishiogu, Arakawa-ku, Tokyo 116-8567, Japan
03-3810-1111
ahirasu@dnh.twmu.ac.jp
Tokyo Women's Medical University
None
Self funding
NO
2015 | Year | 05 | Month | 14 | Day |
Partially published
Completed
2004 | Year | 07 | Month | 01 | Day |
2004 | Year | 07 | Month | 26 | Day |
2015 | Year | 04 | Month | 01 | Day |
2015 | Year | 04 | Month | 01 | Day |
2015 | Year | 05 | Month | 14 | Day |
2015 | Year | 05 | Month | 14 | Day |
2015 | Year | 05 | Month | 14 | Day |
2015 | Year | 05 | Month | 14 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000020360
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