Unique ID issued by UMIN | UMIN000017798 |
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Receipt number | R000020620 |
Scientific Title | Study for efficacy of DPP-4 inhibitor to mytonic dystrophy complicated diabetes mellitus by continuous glucose monitoring (CGM) |
Date of disclosure of the study information | 2015/06/15 |
Last modified on | 2018/12/08 10:17:40 |
Study for efficacy of DPP-4 inhibitor to mytonic dystrophy complicated diabetes mellitus by continuous glucose monitoring (CGM)
DPP-4 inhibitor to myotonic dystrophy: CGM observational study
Study for efficacy of DPP-4 inhibitor to mytonic dystrophy complicated diabetes mellitus by continuous glucose monitoring (CGM)
DPP-4 inhibitor to myotonic dystrophy: CGM observational study
Japan |
Myotonic dystrophy type 1
Endocrinology and Metabolism | Neurology |
Others
YES
To evaluate efficacy of DPP-4 inhibitor against myotonic dystrophy complicated diabetes mellitus.
Safety,Efficacy
Others
Others
Not applicable
Evaluation before and after administration of DPP-4 inhibitor.
Index by CGM (mean blood sugar (BS), SD of BS, M value, MAGE, BS area, proportion of hypoglycemia or hyperglycemia) and routine blood examination.
Adverse event
Observational
20 | years-old | <= |
75 | years-old | > |
Male and Female
1.Genetically diagnosed
2.Fasting BS > 130mg/dl or 7.0% < HbA1c < 10.0%
3.Fasting serum C-peptide > 1.0mg/ml
4.Oral intake
5.Without limitation for stage or severity of disease
1.Medicated by insulin, DPP-4 inhibitor or GLP-1 agonist
2.Serious infection, perioperative
or serious injury
3.Cardio-vascular event
4.Proronged QT on ECG
5.Serious liver damage
6.Moderate or serious renal damage
7.Moderate or serious heart failure
8.Gestation or lactation period
9.Short bowel syndrome
10.Medicated by steroid, interferon, hormonal agent, atypical antipsychotic, IA antiarrhythmic agent or III antiarrhythmic agent
11.Emaciation or skin disease with difficulty to be attached CGM
12.No informed consent with a form
13.Assessed as inadequate by a physician in charge
40
1st name | |
Middle name | |
Last name | Hiroto TAKADA |
National Aomori Hospital
Neurology
155-1 Namioka-Megasawa-Hirano, Aomori, Japan
+81-172-62-405
takada@aomorihosp.jp
1st name | |
Middle name | |
Last name | Hiroto TAKADA |
National Aomori Hospital
Neurology
155-1 Namioka-Megasawa-Hirano, Aomori, Japan
+81-172-62-405
http://plaza.umin.ac.jp/~DM-CTG/index.html
takada@aomorihosp.jp
Dystrophia Myotonica: Clinical Treatment Group
MHLW(Japan)
Health and labor science research
Japan
NO
国立病院機構青森病院(青森県)Aomori National Hospital
国立病院機構刀根山病院(大阪府)Toneyama National Hospital
国立病院機構大牟田病院(福岡県)Omuta National Hospital
国立病院機構兵庫中央病院(兵庫県)Hyogo-chuo National Hospital
国立病院機構旭川医療センター(北海道)Asahikawa National Hospital
大阪大学大学院医学研究科(大阪府)Graduate school of medicine Osaka University
2015 | Year | 06 | Month | 15 | Day |
http://plaza.umin.ac.jp/~DM-CTG/index.html
Unpublished
Preinitiation
2015 | Year | 04 | Month | 16 | Day |
2015 | Year | 06 | Month | 15 | Day |
2019 | Year | 03 | Month | 31 | Day |
2019 | Year | 03 | Month | 31 | Day |
2019 | Year | 03 | Month | 31 | Day |
2019 | Year | 12 | Month | 31 | Day |
Index by CGM (mean blood sugar (BS), SD of BS, M value, MAGE, BS area, proportion of hypoglycemia or hyperglycemia) and routine blood examination are observed.
2015 | Year | 06 | Month | 03 | Day |
2018 | Year | 12 | Month | 08 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000020620
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