Unique ID issued by UMIN | UMIN000018119 |
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Receipt number | R000020831 |
Scientific Title | Multicenter evaluation of the Verigene Gram-Negative Blood Culture Nucleic Acid Test on the impact of resistance gene determinant for the prediction of susceptibility of Enterobacteriaceae to third-generation cephalosporin in Japan |
Date of disclosure of the study information | 2015/06/30 |
Last modified on | 2016/11/25 13:38:34 |
Multicenter evaluation of the Verigene Gram-Negative Blood Culture Nucleic Acid Test on the impact of resistance gene determinant for the prediction of susceptibility of Enterobacteriaceae to third-generation cephalosporin in Japan
Gram negative bacteremia (Escherichia coli, Klebsiella pneumoniae, Klebsiella oxytoca or Proteus spp.)
Multicenter evaluation of the Verigene Gram-Negative Blood Culture Nucleic Acid Test on the impact of resistance gene determinant for the prediction of susceptibility of Enterobacteriaceae to third-generation cephalosporin in Japan
Gram negative bacteremia (Escherichia coli, Klebsiella pneumoniae, Klebsiella oxytoca or Proteus spp.)
Japan |
Gram negative bacteremia (Escherichia coli, Klebsiella pneumoniae, Klebsiella oxytoca or Proteus spp.)
Infectious disease | Laboratory medicine |
Others
NO
Evaluation of the Verigene Gram-Negative Blood Culture Nucleic Acid Test on the impact of resistance gene determinant for the prediction of susceptibility of Enterobacteriaceae to third-generation cephalosporin
Others
Clinical evaluation
Confirmatory
Others
Not applicable
Cefotaxime susceptibility of Escherichia coli, Klebsiella pneumoniae, Klebsiella oxytoca, Proteus spp. when resistance genes are not detected by Verigene system with BC-GN panel
(i)Susceptibility of each Enterobacteriaceae to cefotaxime when resistance genes are not detected by Verigene system with BC-GN panel
(ii)Detection rate of resistance genes by Verigene BC-GN panel among each
Enterobacteriaceae with non-susceptible to cefotaxime
(iii)Antimicrobial susceptibilities of each Enterobacteriaceae when blaCTX-M is detected by Verigene system with BC-GN panel
Observational
Not applicable |
Not applicable |
Male and Female
(i)Tsukuba Medical Center Hospital
The blood of Gram negative bacteremia detected by the BacT/ALERT 3D system
(ii)Other hospitals or the Miroku Medical Laboratory
Strains of Escherichia coli, Klebsiella pneumoniae, Klebsiella oxytoca or Proteus spp. without in vitro susceptibility to third-generation cephalosporin (cefotaxime MIC = 2ug/mL or more) isolated from the blood of positive blood culture bottles incubated by automated blood culture systems.
(i) If strains and patient information are not available for clinical research purpose
(ii) If evaluation with Verigene system is not able to be performed
100
1st name | |
Middle name | |
Last name | Hiromichi Suzuki |
Tsukuba Medical Center Hospital
Division of Infectious Diseases, Department of Medicine/Department of Clinical Laboratory Medicine
1-3-1 Amakubo, Tsukuba, Ibaraki
81-29-851-3511
hsuzuki@tmch.or.jp
1st name | |
Middle name | |
Last name | Hiromichi Suzuki |
Tsukuba Medical Center Hospital
Division of Infectious Diseases, Department of Medicine/Department of Clinical Laboratory Medicine
1-3-1 Amakubo, Tsukuba, Ibaraki
81-29-851-3511
hsuzuki@tmch.or.jp
Tsukuba Medical Center Hospital
Hitachi High-Technologies Corporation
Profit organization
Japan
Tsukuba Medical Center Hospital
Seirei Hamamatsu General Hospital
Seirei Mikatahara General Hospital
Hitachi General Hospital
Chutoen General Medical Center
Akashi Medical Center
Miroku Medical Laboratory Inc.
Tsukuba Medical Center Hospital
NO
筑波メディカルセンター病院(茨城県)、聖隷浜松病院(静岡県)、聖隷三方原病院(静岡県)、日立総合病院(茨城県)、中東遠総合医療センター(静岡県)、明石医療センター(兵庫県)、株式会社ミロクメディカルラボラトリー(長野県)
2015 | Year | 06 | Month | 30 | Day |
Unpublished
Completed
2015 | Year | 05 | Month | 30 | Day |
2015 | Year | 07 | Month | 01 | Day |
Prospective observational study
2015 | Year | 06 | Month | 29 | Day |
2016 | Year | 11 | Month | 25 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000020831
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