Unique ID issued by UMIN | UMIN000018264 |
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Receipt number | R000021118 |
Scientific Title | Availability of soluble PD-L1 as a biomaker that predicts the response of therapy with anti-PD-1 antibody for the patients with malignant melanoma |
Date of disclosure of the study information | 2015/10/01 |
Last modified on | 2016/03/08 12:51:50 |
Availability of soluble PD-L1 as a biomaker that predicts the response of therapy with anti-PD-1 antibody for the patients with malignant melanoma
Investigation of biomakers that predicts the response of therapy with anti-PD-1 antibody for the patients with malignant melanoma
Availability of soluble PD-L1 as a biomaker that predicts the response of therapy with anti-PD-1 antibody for the patients with malignant melanoma
Investigation of biomakers that predicts the response of therapy with anti-PD-1 antibody for the patients with malignant melanoma
Japan |
Malignant melanoma
Dermatology |
Malignancy
NO
To examine the efficacy of soluble PD-L1 as a biomaker of therapeutic response with anti-PD-1 antibody for the patients with malignant melanoma
Efficacy
Confirmatory
Others
Not applicable
tumor size, sites, sum of the tumor size (representative of five), serum concentration of soluble PD-L1
patients' background
serum concentration of LDH and 5-SCD
Observational
20 | years-old | <= |
Not applicable |
Male and Female
1) patients who were diagnosed as malignant melanoma and unable to remove tumors surgically.
2) patients whose age are more than 20y
3) patients who agree to register this study after an informed concent
1) patients who offer withdrawal from the entry of this study
2) patients whose age are under 20y
3) patients with multiple cancers
4) patients who have allergy to anti-PD-1 antibody
5) patients who received other immune therapy than anti-PD-1 antibody
30
1st name | |
Middle name | |
Last name | Shimpei Kasagi |
Kobe university hospital
Department of laboratory medicine
7-5-2 Kusunoki-cho, Tyuo-ku, Kobe, Hyogo, Japan
081-78-382-6312
kobe470@med.kobe-u.ac.jp
1st name | |
Middle name | |
Last name | Shimpei Kasagi |
Kobe university hospital
Department of laboratory medicine
Department of laboratory medicine
081-78-382-6312
kobe470@med.kobe-u.ac.jp
Kobe university hospital
Department of laboratory medicine
ONO PHARMACEUTICAL CO.LTD
Bristol-Myers Squibb
Profit organization
JAPAN
Kobe university hospital, Department of Dermatology
Hyogo Cancer Center, Department of Dermatology
Charitable Trust Laboratory Medicine Research Foundation of Japan
NO
神戸大学医学部附属病院(兵庫県)
2015 | Year | 10 | Month | 01 | Day |
Unpublished
Open public recruiting
2015 | Year | 07 | Month | 08 | Day |
2015 | Year | 10 | Month | 01 | Day |
2018 | Year | 10 | Month | 01 | Day |
2018 | Year | 10 | Month | 01 | Day |
2018 | Year | 10 | Month | 01 | Day |
2018 | Year | 12 | Month | 31 | Day |
In this study, we will evaluate the efficacy of soluble PD-L1 as a biomaker that predicts therapeutic response of anti-PD-1 antibody for the patients with
malignant melanoma
2015 | Year | 07 | Month | 10 | Day |
2016 | Year | 03 | Month | 08 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000021118
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