Unique ID issued by UMIN | UMIN000019082 |
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Receipt number | R000021483 |
Scientific Title | the effect of smell dysfunction using hydrogen gas for parkinson disease |
Date of disclosure of the study information | 2015/09/22 |
Last modified on | 2018/03/23 09:40:05 |
the effect of smell dysfunction using hydrogen gas for parkinson disease
the effect of smell dysfunction using hydrogen gas for parkinson disease
the effect of smell dysfunction using hydrogen gas for parkinson disease
the effect of smell dysfunction using hydrogen gas for parkinson disease
Japan |
parkinson's disease
Neurology |
Others
NO
to evaluate the effect of hydrogen gas for smell dysfunction in parkinson's disease
Efficacy
The primary endpoint with efficacy in PD was the change of smell test(OSIT-J) and urin 8-8OHdG from baseline to the one month.smell test and Urinary 8-OHdG were measured before treatment and after one month of intervention trial. then two months of discontinuation of the intervention was done. smell test and Urinary 8-OHdG were measured before treatment and after one month of intervention trial.
Interventional
Cross-over
Randomized
Individual
Double blind -all involved are blinded
Placebo
YES
YES
Institution is not considered as adjustment factor.
YES
Central registration
2
Treatment
Medicine |
we measured smell test and urine 8-OHdG before and after 3.5% hydrogen gas. After two month discontinuation of administration. we measured smell test and urine 8-OHdG before and after room air.
we measured smell test and urine 8-OHdG before and after room air. After two month discontinuation of administration. we measured smell test and urine 8-OHdG before and after 3.5% hydrogen gas.
Not applicable |
Not applicable |
Male and Female
parkinson's disease
no limitation ofsex, age
The patients who could not use the tools.
The patients who did not obtain consent.
The patients who have vascular disease, DM, nose disordes.
20
1st name | |
Middle name | |
Last name | Masaki Hirayama |
Nagoya University Graduate School of Medicine
department of clinical laboratory
Daiko-Minami, Higashi-ku, Nagoya City, Aichi Prefecture
0527191184
hirasan@med.nagoya-u.ac.jp
1st name | |
Middle name | |
Last name | Masaaki Hirayama |
Nagoya University Graduate School of Medicine
department of clinical laboratory
Daiko-Minami, Higashi-ku, Nagoya City, Aichi Prefecture
0527191184
hirasan@med.nagoya-u.ac.jp
Nagoya University Graduate School of Medicine
Nagoya University Graduate School of Medicine
Self funding
NO
2015 | Year | 09 | Month | 22 | Day |
Unpublished
there are no effect to improve smell function in Parkinson's disease patients.
The level of urine 8-OHdG slightly increase using hydrogen gas.
Completed
2015 | Year | 08 | Month | 20 | Day |
2015 | Year | 10 | Month | 10 | Day |
2017 | Year | 10 | Month | 10 | Day |
2018 | Year | 03 | Month | 01 | Day |
2018 | Year | 03 | Month | 01 | Day |
2018 | Year | 03 | Month | 21 | Day |
2015 | Year | 09 | Month | 20 | Day |
2018 | Year | 03 | Month | 23 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000021483
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