Unique ID issued by UMIN | UMIN000019042 |
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Receipt number | R000022017 |
Scientific Title | Effect of tiotropium versus montelukast on airway inflammation and remodeling in asthma |
Date of disclosure of the study information | 2015/09/24 |
Last modified on | 2018/09/26 17:02:52 |
Effect of tiotropium versus montelukast on airway inflammation and remodeling in asthma
Effect of tiotropium versus montelukast on airway inflammation and remodeling in asthma
Effect of tiotropium versus montelukast on airway inflammation and remodeling in asthma
Effect of tiotropium versus montelukast on airway inflammation and remodeling in asthma
Japan |
Bronchial asthma
Pneumology |
Others
NO
To investigate the efficacy of tiotropium on clinical index of asthma comapred with montelukast
Efficacy
Confirmatory
Explanatory
Not applicable
Indices of chest CT, FeNO(baseline and after 6 months treatment)
Parameters of pulmonary function
Cell counts of induced sputum
Scores of quality of life
Interventional
Parallel
Randomized
Individual
Open -but assessor(s) are blinded
Active
2
Treatment
Medicine |
Tiotropium treatment group
Respimat (2.5mcg) 2 inhalation once daily
Treatment period 6 months
Montelukast treatment group
Kipres (10mg) oral once daily
Treatment period 6 months
16 | years-old | < |
Not applicable |
Male and Female
Symptomatic asthma patients who have been treated with ICS+LABA
1. Patients who have any coexisting pulmonary diseases other than asthma
2. Pregnancy or lactation
3. Patients have hypersensitivity to tiotropium or montelukast
4. Patients judged to be unsuitable by the doctors
100
1st name | |
Middle name | |
Last name | Makoto Hoshino |
Atami Hospital
International University of Health and Welfare
Division of Clinical Allergy, Department of Internal Medicine
13-1 Higashikaigan-cho, Atami, Shizuoka
0557-81-9171
hoshino@iuhw.ac.jp
1st name | |
Middle name | |
Last name | Makoto Hoshino |
Atami Hospital, International University of Health and Welfare
Division of Clinical Allergy, Department of Internal Medicine
13-1 Higashikaigan-cho, Atami, Shizuoka
0557-81-9171
hoshino@iuhw.ac.jp
Atami Hospital
International University of Health and Welfare
none
Self funding
NO
2015 | Year | 09 | Month | 24 | Day |
Unpublished
Completed
2014 | Year | 11 | Month | 27 | Day |
2015 | Year | 01 | Month | 01 | Day |
2016 | Year | 03 | Month | 31 | Day |
2018 | Year | 08 | Month | 10 | Day |
2015 | Year | 09 | Month | 16 | Day |
2018 | Year | 09 | Month | 26 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000022017
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