Unique ID issued by UMIN | UMIN000019048 |
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Receipt number | R000022026 |
Scientific Title | Influence of the formulationC4W on epidermis. |
Date of disclosure of the study information | 2015/09/17 |
Last modified on | 2016/03/10 16:17:57 |
Influence of the formulationC4W on epidermis.
Influence of the formulationC4W on epidermis.
Influence of the formulationC4W on epidermis.
Influence of the formulationC4W on epidermis.
Japan |
Healthy adults
Dermatology | Adult |
Others
NO
To evaluate the changes of physiological properties of the skin in healthy subjects by application of active ingredient.
Efficacy
-Change of water content in stratum corneum after the topical application for 4 weeks
-Change of NMF content in stratum corneum after the topical application for 4 weeks
-Change of epidermal thickness
-Morphological change of epidermal cells
-Change of the properties of fluorescence from epidermis
-Change of the blood flow in skin
-Change of the melanin content in epidermis
Interventional
Single arm
Non-randomized
Open -no one is blinded
Self control
1
Treatment
Other |
Apply the formulation including an active ingredient and placebo to both forearm skin respectively twice daily for 4 weeks
20 | years-old | <= |
59 | years-old | >= |
Male
Healthy male
-Subjects with cutaneous symptoms of atopic dermatitis
-Subjects regularly going to hospital for sickness
-Subjects undergoing hormone therapy
- Subjects who are taking OCT or prescription medicine
-Subjects with clinically-significant disorder (eczema, a scratch etc.) at the sites to be studied
-Subjects participation in another clinical study accompanied by topical application of formulations and tape stripping or delipidation treatment to obtain experimental dry skin to the sites to be studied within the past 1 month.
-Subjects take carbon dioxide bath or carbonated spring within the past 1 month.
-Subjects deemed inappropriate to participate in this study by the principle investigator
10
1st name | |
Middle name | |
Last name | Takatoshi Murase |
Kao Corporation
R&D -Core Technology- Biological Science Research
2606, Akabane, Ichikai-machi, haga-gun, Tochigi, 321-3497, JAPAN
0285-68-7871
murase.takatoshi@kao.co.jp
1st name | |
Middle name | |
Last name | Keiichi Sugata |
Kao Corporation
R&D -Core Technology- Biological Science Research
2606, Akabane, Ichikai-machi, haga-gun, Tochigi, 321-3497, JAPAN
0285-68-7872
sugata.keiichi@kao.co.jp
Kao Corporation
Kao Corporation
Profit organization
NO
花王株式会社栃木事業場生理機能棟(栃木)
2015 | Year | 09 | Month | 17 | Day |
Unpublished
Completed
2015 | Year | 09 | Month | 16 | Day |
2015 | Year | 09 | Month | 18 | Day |
2016 | Year | 03 | Month | 10 | Day |
2016 | Year | 03 | Month | 10 | Day |
2015 | Year | 09 | Month | 17 | Day |
2016 | Year | 03 | Month | 10 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000022026
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