Unique ID issued by UMIN | UMIN000019116 |
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Receipt number | R000022100 |
Scientific Title | Research on foods for stress relief (3) |
Date of disclosure of the study information | 2015/10/01 |
Last modified on | 2017/05/16 11:40:50 |
Research on foods for stress relief (3)
Research on foods for stress relief (3)
Research on foods for stress relief (3)
Research on foods for stress relief (3)
Japan |
Stress-related mental or physical disorders
Medicine in general |
Others
NO
Effects of fermented milk drinks on states of stress-related mental or physical disorders
Efficacy
Confirmatory
Not applicable
Effects of fermented milk drinks on stress-related sleep disorders at 6, 8, 9, and 11 weeks into intervention
Effects of fermented milk drinks on stress-related sleep disorders
Interventional
Parallel
Randomized
Individual
Double blind -all involved are blinded
Placebo
2
Prevention
Food |
Daily intakes of fermented milk drinks including Lactobacillus casei strain Shirota for 8 weeks before Computer based testing (CBT) and 3 weeks after CBT
Daily intakes of placebo drinks without Lactobacillus casei strain Shirota for 8 weeks before CBT and 2 weeks after CBT
20 | years-old | <= |
Not applicable |
Male and Female
Subjects are 4th grade medical students who are in good physical health.
1. Persons having history of psychiatric or somatic diseases in the past and present.
2. Persons taking medication at least for three months prior to the enrollment and during the experimental period.
3. Smokers.
4. Persons having allergy disease, including with dairy products.
60
1st name | |
Middle name | |
Last name | Kazuhito Rokutan |
Tokushima University Graduate School
Dept. of Pathophysiology, Inst. of Biomedical Sciences
3-18-15 Kuramoto-cho, Tokushima
088-633-9004
stress.sci@tokushima-u.ac.jp
1st name | |
Middle name | |
Last name | Kensei Nishida |
Tokushima University Graduate School
Dept. of Pathophysiology, Inst. of Biomedical Sciences
3-18-15 Kuramoto-cho, Tokushima
088-633-9004
knishida@tokushima-u.ac.jp
Tokushima University
Yakult Honsha Co., Ltd.
Profit organization
NO
2015 | Year | 10 | Month | 01 | Day |
Published
To investigate the effects of the probiotic Lactobacillus casei strain Shirota on abdominal dysfunction, a double-blind, placebo-controlled trial was conducted with healthy medical students undertaking an authorized nationwide examination for academic advancement.
1. Stress-induced sleep disturbance was improved in the L. casei strain Shirota group.
2. Delta power during the first sleep cycle, measured as an index of sleep intensity, increased as the exam approached in the LcS group and was significantly higher than in the placebo group.
Main results already published
2015 | Year | 09 | Month | 02 | Day |
2015 | Year | 10 | Month | 09 | Day |
2016 | Year | 03 | Month | 31 | Day |
2016 | Year | 06 | Month | 01 | Day |
2016 | Year | 06 | Month | 01 | Day |
2016 | Year | 09 | Month | 01 | Day |
Benef Microbes. 2017 Apr 26;8(2):153-162. doi: 10.3920/BM2016.0150.
2015 | Year | 09 | Month | 25 | Day |
2017 | Year | 05 | Month | 16 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000022100
Research Plan | |
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