Unique ID issued by UMIN | UMIN000019365 |
---|---|
Receipt number | R000022181 |
Scientific Title | Dialyzability of faropenem sodium during hemodialysis in patients with chronic renal failure |
Date of disclosure of the study information | 2015/10/17 |
Last modified on | 2017/11/15 09:47:04 |
Dialyzability of faropenem sodium during hemodialysis in patients with chronic renal failure
Dialyzability of faropenem sodium during hemodialysis
Dialyzability of faropenem sodium during hemodialysis in patients with chronic renal failure
Dialyzability of faropenem sodium during hemodialysis
Japan |
Chronic renal failure, infection
Medicine in general | Nephrology |
Others
NO
To clarify the pharmacokinetics and dialyzability of faropenem during hemodialysis
Pharmacokinetics
Hemodialysis clearance of faropenem
Interventional
Single arm
Non-randomized
Open -no one is blinded
Uncontrolled
1
Treatment
Medicine |
To measure the concentration of faropenem, blood samples were collected from both the pre- and post-dialyzer lines before, and at 2 and 4 hr after hemodialysis.
20 | years-old | <= |
Not applicable |
Male and Female
1. Hemodialysis has been carried out due to chronic renal failure
2. Hemodialysis was carried out continuously for more than one month
3. Faropenem is adapted
1. Patients with poorly controlled diabetes (HbA1c 7.0% or more)
2. Patients with hepatic failure
3. Patients have a history of allergy to beta-lactam antibiotics
4. Patients have been taking faropenem within one week
5. Patients taking sodium valproate
6. Patients taking warfarin
7. Pregnant women and nursing woman
8. Judged inappropriate to participate in this study by a doctor
10
1st name | |
Middle name | |
Last name | Akio Fujimura |
Jichi Medical University
Division of Clinical Pharmacology, Department of Pharmacology
3311-1 Yakushiji, Shimotsuke, Tochigi
0285-58-7388
akiofuji@jichi.ac.jp
1st name | |
Middle name | |
Last name | Kentaro Ushijima |
Jichi Medical University
Division of Clinical Pharmacology, Department of Pharmacology
3311-1 Yakushiji, Shimotsuke, Tochigi
0285-58-7388
ushijima-kentarou@umin.ac.jp
Division of Clinical Pharmacology, Department of Pharmacology, Jichi Medical University
Jichi Medical University
Self funding
NO
真岡病院(真岡市)、笠岡第一病院(笠岡市)
2015 | Year | 10 | Month | 17 | Day |
Published
https://www.ncbi.nlm.nih.gov/pubmed/27629941
The elimination ratio of faropenem by hemodialysis was small as about 20%; In the 29th Annual Meeting of the Japanese Society of Clinical Pharmacology and Therapeutics (Tokyo, Dec 4th -6th, 2008)
Completed
2006 | Year | 09 | Month | 05 | Day |
2006 | Year | 12 | Month | 11 | Day |
2015 | Year | 10 | Month | 15 | Day |
2017 | Year | 11 | Month | 15 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000022181
Research Plan | |
---|---|
Registered date | File name |
Research case data specifications | |
---|---|
Registered date | File name |
Research case data | |
---|---|
Registered date | File name |