Unique ID issued by UMIN | UMIN000019780 |
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Receipt number | R000022847 |
Scientific Title | Chemotherapy for osteoradionecrosis of mandible using a pentoxifylline-tocopherol-clodronate combination (PENTOCLO). |
Date of disclosure of the study information | 2015/11/13 |
Last modified on | 2021/09/15 18:09:23 |
Chemotherapy for osteoradionecrosis of mandible using a pentoxifylline-tocopherol-clodronate combination (PENTOCLO).
Chemotherapy for osteoradionecrosis using PENTOCLO
Chemotherapy for osteoradionecrosis of mandible using a pentoxifylline-tocopherol-clodronate combination (PENTOCLO).
Chemotherapy for osteoradionecrosis using PENTOCLO
Japan |
Osteoradionecrosis of the mandible
Oral surgery |
Malignancy
NO
To heal osteoradionecrosis of the mandible which usually requires segmental bone resection using a pentoxifylline-tocopherol-clodronate combination.
Efficacy
Sequestration with oral mucosal and cutaneous healing
Interventional
Single arm
Non-randomized
Open -no one is blinded
Historical
1
Treatment
Medicine |
Pentoxifillyne 800mg/day 5 days in a week 1 year
Clodoronate 1600mg/day 7 days in a week 1 year
Tocopherol 1g/day 7days in a week 1 year
0 | years-old | <= |
Not applicable |
Male and Female
Osteoradionecrosis with oral mucosal and/or skin defect with or without pus discharging.
A patient with gastrointestinal disease
20
1st name | |
Middle name | |
Last name | Hirota, Makoto |
Yokohama City University
Oral and Maxillofacial Surgery
3-9 Fukuura, Kanazawaku, Yokohama City
045-787-2800
mhirota@yokohama-cu.ac.jp
1st name | |
Middle name | |
Last name | Hirota, Makoto |
Yokohama City University
Oral and Maxillofacial Surgery
3-9 Fukuura, Kanazawaku, Yokohama City
045-787-2800
mhirota@yokohama-cu.ac.jp
Yokohama City University
Yokohama City University
Self funding
NO
2015 | Year | 11 | Month | 13 | Day |
Unpublished
Completed
2015 | Year | 04 | Month | 21 | Day |
2015 | Year | 10 | Month | 01 | Day |
2015 | Year | 10 | Month | 01 | Day |
2019 | Year | 03 | Month | 31 | Day |
2015 | Year | 11 | Month | 13 | Day |
2021 | Year | 09 | Month | 15 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000022847
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