Unique ID issued by UMIN | UMIN000019963 |
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Receipt number | R000023049 |
Scientific Title | Evaluation of brain functional connectivity using resting state fMRI in idiopathic normal pressure hydrocephalus patients after lumboperitoneal shunt. |
Date of disclosure of the study information | 2015/11/30 |
Last modified on | 2020/06/02 10:50:11 |
Evaluation of brain functional connectivity using resting state fMRI in idiopathic normal pressure hydrocephalus patients after lumboperitoneal shunt.
Evaluation of brain functional connectivity in idiopathic normal pressure hydrocephalus patients after lumboperitoneal shunt.
Evaluation of brain functional connectivity using resting state fMRI in idiopathic normal pressure hydrocephalus patients after lumboperitoneal shunt.
Evaluation of brain functional connectivity in idiopathic normal pressure hydrocephalus patients after lumboperitoneal shunt.
Japan |
idiopathic normal pressure hydrocephalus
Neurosurgery | Adult |
Others
NO
The aim of this study is to evaluate the functional MRI before and after shunt surgery in idiopathic hydrocephalus. We will bring out the change of default mode network, salience network and executive control network before and after surgery.
Others
To evaluate the change of fMRI after improvement of cognitive function.
Exploratory
Others
Not applicable
We will evaluate functional MRI and motor and cognitive function before and 2 months after surgery.
cognitive function(ACE-3, MMSE, FAB, WAIS-R, ADAS, WMS-R, TMT), motor function( Timed Up&Go test), functional MRI
Interventional
Single arm
Non-randomized
Open -no one is blinded
Self control
1
Diagnosis
Other |
Functional MRI will be performed before and 2months after surgery.
60 | years-old | <= |
80 | years-old | >= |
Male and Female
Patients with idiopathic normal pressure hydrocephalus. Patients with good enough cognitive function for the agreement of this study.
Untolerable for MRI study.
20
1st name | Kazuhito |
Middle name | |
Last name | Takeuchi |
Nagoya University
Department of Neurosurgery
466-8550
65 tsurumai, syowa-ku, nagoya, Aichi
052-744-2353
mail@wajit.com
1st name | Kazuhito |
Middle name | |
Last name | Takeuchi |
Nagoya University
Department of Neurosurgery
466-8550
65 tsurumai, syowa-ku, nagoya, Aichi
052-744-2353
mail@wajit.com
Department of Neurosurgery, Nagoya University
Department of Neurosurgery, Nagoya University
Other
Nagoya University
65 tsurumai, Showa, Nagoya, Aichi
052-744-2360
ktakeuchi@med.nagoya-u.ac.jp
NO
名古屋大学病院
2015 | Year | 11 | Month | 30 | Day |
2018/4/1
Unpublished
2018/4/1
6
It was discontinued due to the difficulty of accumulating the number of cases and the difficulty of maintaining and sustaining the test.
2020 | Year | 06 | Month | 02 | Day |
It was cancelled because of the difficulty in securing the number of patients with normal pressure hydrocephalus.
Discontinuation
None
The number of cases that could be analyzed was not reached.
Open public recruiting
2015 | Year | 05 | Month | 27 | Day |
2015 | Year | 05 | Month | 27 | Day |
2015 | Year | 05 | Month | 27 | Day |
2018 | Year | 04 | Month | 01 | Day |
2018 | Year | 04 | Month | 01 | Day |
2018 | Year | 04 | Month | 01 | Day |
2018 | Year | 04 | Month | 01 | Day |
2015 | Year | 11 | Month | 27 | Day |
2020 | Year | 06 | Month | 02 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000023049
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