Unique ID issued by UMIN | UMIN000020219 |
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Receipt number | R000023351 |
Scientific Title | To evaluate the outcomes of a novel ET method which double embryos transferred to the separate position on DET (s-DET) compared to those of the conventional DET (c-DET) in Assisted Reproductive Technology (ART) treatment |
Date of disclosure of the study information | 2015/12/16 |
Last modified on | 2016/12/20 12:37:51 |
To evaluate the outcomes of a novel ET method which double embryos transferred to the separate position on DET (s-DET) compared to those of the conventional DET (c-DET) in Assisted Reproductive Technology (ART) treatment
To evaluate the outcomes of a novel ET method which double embryos transferred to the separate position on DET
To evaluate the outcomes of a novel ET method which double embryos transferred to the separate position on DET (s-DET) compared to those of the conventional DET (c-DET) in Assisted Reproductive Technology (ART) treatment
To evaluate the outcomes of a novel ET method which double embryos transferred to the separate position on DET
Japan |
infertility
Obstetrics and Gynecology |
Others
NO
To evaluate the outcomes of a novel embryo transfer (ET) method in which double embryos are transferred separately (s-DET) compared with those of conventional DET (c-DET).
Efficacy
Reproductive outcomes including human chorionic gonadotropin levels, gestational sac development, and clinical pregnancy, implantation, multiple pregnancy, and miscarriage rates were compared between the s-DET and c-DET groups.
Interventional
Parallel
Non-randomized
Open -no one is blinded
Active
2
Prevention
Maneuver |
Some patients underwent s-DET in which two embryos were transferred separately.
Other patients underwent c-DET in which two embryos were transferred together.
Not applicable |
Not applicable |
Female
Study patients are selected if they are eligible for in vitro fertilization (IVF)/ET and had a history of two or more failed IVF/ET cycles with morphologically and developmentally average to good quality embryos transferred into an adequately prepared endometrium.
None of the patients have submucosal fibroids, endometrial polyps, intrauterine adhesions, congenital anomalies of the uterus, or hydrosalpinges. In addition, none of the patients have any history of or an active autoimmune disease.
500
1st name | |
Middle name | |
Last name | TOMOYA HASEGAWA |
Tokyo Medical University
Department of Obstetrics and Gynecology
6-7-1, Nishi-Shinjyuku, Shinjyuku, Tokyo, 160-0023, Japan
03-3342-6111
ppppq999@gmail.com
1st name | |
Middle name | |
Last name | TOMOYA HASEGAWA |
Tokyo Medical University
Department of Obstetrics and Gynecology
6-7-1, Nishi-Shinjyuku, Shinjyuku, Tokyo, 160-0023, Japan
03-3342-6111
ppppq999@gmail.com
Tokyo Medical University
None
Self funding
NO
Sugiyama Clinic
2015 | Year | 12 | Month | 16 | Day |
Published
We found that clinical pregnancy and implantation rates in s-DET group were 25.5% and 13.1%, respectively, which were similar to those in c-DET group (24.2% and 14.9%, respectively). However, multiple pregnancy rate was 2.9% in s-DET group, significantly lower than that in c-DET group (23.5%; P < 0.01). Although s-DET is similar to c-DET, except that double embryos are separately transferred, multiple pregnancy rate in s-DET group was significantly lower than that in c-DET group. Therefore, s-DET may become a novel method to prevent multiple gestations.
Completed
2015 | Year | 04 | Month | 20 | Day |
2015 | Year | 05 | Month | 01 | Day |
2016 | Year | 04 | Month | 01 | Day |
2016 | Year | 10 | Month | 10 | Day |
2016 | Year | 10 | Month | 22 | Day |
2016 | Year | 10 | Month | 30 | Day |
2015 | Year | 12 | Month | 16 | Day |
2016 | Year | 12 | Month | 20 | Day |
Value
https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000023351
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