UMIN-CTR Clinical Trial

BACK TOP
UMIN-CTR English Home Glossary (Simple) FAQ Search clinical trials

Name:
UMIN ID:

Recruitment status Open public recruiting
Unique ID issued by UMIN UMIN000022957
Receipt No. R000023404
Scientific Title Detection of impaired neural circuits in central nervous system diseases and development of neurophysiological biomarkers for functional brain network abnormalities
Date of disclosure of the study information 2016/06/30
Last modified on 2016/06/30

* This page includes information on clinical trials registered in UMIN clinical trial registed system.
* We don't aim to advertise certain products or treatments


Basic information
Public title Detection of impaired neural circuits in central nervous system diseases and development of neurophysiological biomarkers for functional brain network abnormalities
Acronym Detection of impaired neural circuits in central nervous system diseases
Scientific Title Detection of impaired neural circuits in central nervous system diseases and development of neurophysiological biomarkers for functional brain network abnormalities
Scientific Title:Acronym Detection of impaired neural circuits in central nervous system diseases
Region
Japan

Condition
Condition cerebrovascular disease, Parkinson's syndrome, essential tremor and epilepsy
Classification by specialty
Neurosurgery
Classification by malignancy Others
Genomic information NO

Objectives
Narrative objectives1 The aim of the study is to detect impaired neural circuits and develop neurophysiological biomarkers for cerebrovascular disease, Parkinson's syndrome, essential tremor and epilepsy, analyzing MRI data and signals of magnetoencephalography and intracranial electrodes.
Basic objectives2 Efficacy
Basic objectives -Others
Trial characteristics_1
Trial characteristics_2
Developmental phase

Assessment
Primary outcomes functional brain networks analyzed using MRI data and signals of magnetoencephalography and intracranial electrodes.
Key secondary outcomes clinical assessment battery for each disease

Base
Study type Observational

Study design
Basic design
Randomization
Randomization unit
Blinding
Control
Stratification
Dynamic allocation
Institution consideration
Blocking
Concealment

Intervention
No. of arms
Purpose of intervention
Type of intervention
Interventions/Control_1
Interventions/Control_2
Interventions/Control_3
Interventions/Control_4
Interventions/Control_5
Interventions/Control_6
Interventions/Control_7
Interventions/Control_8
Interventions/Control_9
Interventions/Control_10

Eligibility
Age-lower limit
18 years-old <=
Age-upper limit

Not applicable
Gender Male and Female
Key inclusion criteria idiopathic Parkinson's disease, essential tremor, acute stroke, normal control
Key exclusion criteria none
Target sample size 60

Research contact person
Name of lead principal investigator
1st name
Middle name
Last name Haruhiko Kishima
Organization Osaka university graduate school of medicine
Division name Department of neurosurgery
Zip code
Address Yamadaoka 2-2, Suita, Osaka
TEL 06-6879-3652
Email hkishima@nsurg.med.osaka-u.ac.jp

Public contact
Name of contact person
1st name
Middle name
Last name Haruhiko Kishima
Organization Osaka university graduate school of medicine
Division name Department of neurosurgery
Zip code
Address Yamadaoka 2-2, Suita, Osaka
TEL 06-6879-3652
Homepage URL
Email hkishima@nsurg.med.osaka-u.ac.jp

Sponsor
Institute Osaka university
Institute
Department

Funding Source
Organization Japan agency for medical research and development
Organization
Division
Category of Funding Organization Japanese Governmental office
Nationality of Funding Organization

Other related organizations
Co-sponsor
Name of secondary funder(s)

IRB Contact (For public release)
Organization
Address
Tel
Email

Secondary IDs
Secondary IDs NO
Study ID_1
Org. issuing International ID_1
Study ID_2
Org. issuing International ID_2
IND to MHLW

Institutions
Institutions 大阪大学医学部附属病院

Other administrative information
Date of disclosure of the study information
2016 Year 06 Month 30 Day

Related information
URL releasing protocol
Publication of results Unpublished

Result
URL related to results and publications
Number of participants that the trial has enrolled
Results
Results date posted
Results Delayed
Results Delay Reason
Date of the first journal publication of results
Baseline Characteristics
Participant flow
Adverse events
Outcome measures
Plan to share IPD
IPD sharing Plan description

Progress
Recruitment status Open public recruiting
Date of protocol fixation
2015 Year 06 Month 17 Day
Date of IRB
Anticipated trial start date
2015 Year 06 Month 17 Day
Last follow-up date
Date of closure to data entry
Date trial data considered complete
Date analysis concluded

Other
Other related information Estimating current sources from the brain magnetic field signals, and analyzing the power and functional connectivity for each frequency band.

Management information
Registered date
2016 Year 06 Month 30 Day
Last modified on
2016 Year 06 Month 30 Day


Link to view the page
URL(English) https://upload.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000023404

Research Plan
Registered date File name

Research case data specifications
Registered date File name

Research case data
Registered date File name


Contact us.